| Objective: This subject is a comparative study of the traditional prescription of Pingweisan and the traditional Chinese medicine Guchang Zhixie Pills,so as to verify the advantages of traditional Chinese medicine in treating diarrhea-type irritable bowel syndrome through the thought of syndrome differentiation and treatment.Qi stagnation and dampness syndrome)provides an effective solution.Methods: Through the method of randomized controlled trials,we selected patients who were treated in the specialist outpatient clinic of our hospital from February 2019 to December 2019,and a total of 72 patients who met this study were selected.The patients were numbered according to the order in which they were treated,and they were evenly divided into a treatment group and a control group using a random number table method.Thirty-six patients in the treatment group were given Pingweisan plus decoction for decoction,and 36 patients in the control group were given Guchang Zhixie Pills for oral administration for 4 weeks(28 days).Before and after treatment,record the patient’s relevant disease information,establish a database,analyze the corresponding data,make a therapeutic evaluation and safety evaluation,to verify the treatment of diarrhea irritable bowel syndrome(Qi stag Block))curative effect and safety.Results: Of the 72 patients in this study,3 patients were lost to follow-up in the treatment group,and 1 patient was voluntarily withdrawn halfway;2 patients were lost to follow-up in the control group,and 1 patient failed to follow the doctor’s orders and took medication on time.A total of 65 patients were finally included in the study..Among these65 patients,there were 32 cases in the treatment group and 33 cases in the control group.After 4 weeks(28 days)of treatment,statistical analysis revealed:1.Comparison of total effectiveness: 5 cases were cured in the treatment group,3 cases were cured in the control group,13 cases were markedly effective in the treatment group,7cases were significantly effective in the control group,9 cases were effective in the treatment group,12 cases were effective in the control group,5 cases were ineffective in the treatment group,and the control group was ineffective 11 cases.The total effective rate of the treatment group reached 84.38%,and the total effective rate of the control group was66.67%.Compared with the total effective rate of the two groups(P <0.05),there was a statistical difference,and the total effective rate of the treatment group was higher.2.TCM symptom score comparison: 32 patients in the treatment group had a score of16.38 ±3.82 before treatment and 5.09 ± 3.92 after treatment;33 patients in the control group had a score of 16.09±3.53 before treatment and a score after treatment 9.06±4.86.Comparison between the treatment group and the control group before and after treatment(P <0.01),that is,the total score of TCM symptoms before and after treatment of the two groups is significantly different.The comparison between the treatment group and the control group after treatment(P <0.01)proved that there was a significant difference in the total scores of TCM symptoms between the two groups after treatment,and the overall symptom improvement in the treatment group was better.3.IBS-SSS score comparison: 32 patients in the treatment group had an IBS-SSS score of 238.28±80.82 before treatment and 69.56±28.27 after treatment;the IBS-SSS score of33 patients in the control group before treatment 228.79±80.80,the score after treatment is112.12±34.30.Comparison between the treatment group and the control group before and after treatment(P <0.01),that is,the IBS-SSS scores of the two groups were significantly different before and after treatment.The treatment group was compared with the control group after treatment(P <0.01),that is,there was a significant difference in the severity of the two groups of patients after treatment.The treatment group was better than the control group after treatment.4.There were no allergies and adverse reactions during the treatment of the two groups of patients,and the related laboratory tests were normal.Conclusion: Ping wei Powder Modified Flavor has a certain clinical effect on the treatment of diarrhea-type irritable bowel syndrome(qi stagnation dampness syndrome),it has a good improvement on the symptoms of diarrhea,abdominal pain and abdominal discomfort,and it has high safety and improves the patient.The quality of life highlights the advantages of traditional Chinese medicine in treating the disease under the guidance of dialectical treatment. |
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