Clinical Study On The Treatment Of Acute Exacerbation Of Chronic Obstructive Pulmonary Disease From The Intestine Based On The "Exterior-interior Relationship Between The Lung And The Large Intestine" Theory

Objective: To observe the clinical efficacy of Xuanbai Chengqi Decoction in treating acute exacerbation of chronic obstructive pulmonary disease from the intestine,and to explore the possible mechanism of action of "intestinal treating" chronic obstructive pulmonary disease in the acute exacerbation period.To provide an objective basis for the clinical application of the theory of "exterior-interior relationship between the lung and the large intestine" in the acute exacerbation of COPD.Methods:Collect 60 patients inpatients in the Department of Respiratory Medicine,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine from February 2019 to January 2020,whose diagnosis met the criteria for the acute exacerbation of chronic obstructive pulmonary disease.At the same time,TCM syndrome differentiation was evidence of pulmonary fever.Sixty patients were randomly divided into a treatment group and a control group,with 30 patients in each group.The control group was treated with conventional Western medicine(general oxygen therapy,antibiotics,phlegm,antispasmodics,hormones,etc.),and the treatment group was treated with Xuanbai Chengqi Decoction on the basis of conventional western medicine treatment,and the course of treatment is 7 days.The TCM syndromes,physical score points,abdominal distension,stool quantification points,lung function,number of days of remission,length of stay,and other related indicators were collected before and after treatment in the two groups of patients.Data analysis was performed using SPSS 26.0 statistical software.Results: 1.Xuanbai Chengqi Decoction combined with conventional western medicine treatment is more effective than traditional western medicine in improving TCM symptom scores,abdominal distension and stool quantitative scores.The results of the two groups are statistically significant(P <0.05).2.The total effective rate ofthe control group was higher than that of the treatment group.The results of the two groups were significantly different(P <0.05).3.In terms of improving lung function,the results of the two groups were not statistically significant(P> 0.05).4.The remission days and length of stay in the treatment group were significantly shorter than those in the control group,and the two were statistically significant(P <0.05).Conclusion: Adding traditional Chinese medicine Xuanbai Chengqi Decoction to the treatment of the acute exacerbation of chronic obstructive pulmonary disease on the basis of conventional Western medicine treatment can better alleviate patients’ related TCM symptoms,improve abdominal distension and stool,and shorten the patient’s remission time and hospitalization.The course of the disease will help the patient to recover quickly,but the effect on the patient’s lung function is not obvious.The mechanism of treating COPD from the intestine is not completely clear.Xuanbai Chengqi Decoction can achieve better clinical efficacy in the treatment of acute exacerbation of COPD,and has no adverse effects.It provides a clinical basis for the treatment of acute exacerbation of COPD from intestinal theory using traditional Chinese medicine.