Observation Of Dexmedetomidine Combined With Sevoflurane Sedation In Pediatric MRI

Objective:To evaluate the the effect of sedation of intranasal dexmedetomidine combination with inhalation sevoflurane for magnetic resonance image?MRI?in pediatric patients.Methods:From January 2019 to June 2019,358 patients aged 1 to 3years were examined by MRI in Children's Hospital affiliated to Chongqing Medical University.According to the sedation scheme,they were divided into two groups:intranasal dexmedetomidine 2ug/kg combination with inhalation sevoflurane?DS group?for 179children.Intranasal dexmedetomidine 2?g/kg combination with oral chloral hydrate 30mg/kg?DC group?for 179 children.Record the success rate of sedation,Induction time?IT?,Total scan time?ST?,Recovery time?RT?,Time to baseline?TTB?.Record the heart rate and the oxygen saturation of immediate administratio?T₀?,the beginning of the inspection?T₁?,5min into the inspection?T₂?,the end of the inspection?T₃?and when they wake up?T₄?.To observe the occurrence of adverse reactions such as bradycardia,hyoxemia,nausea,vomiting and restlessness after administration.Results:There was no significant difference in the age,weight,gender composition and vital signs during sedation between the two groups?P<0.05?.The success rate of sedation in DS group was 97.21%,significantly higher than 90.50%in DC group?P<0.05?.The number of repeated scanning sequences,IT,RT,ST,TTB and the incidence of adverse events in DC group were significantly increased than that in DS group?P<0.05?.The compliance and degree of satisfaction in DS group were significantly increased than DC group?P<0.05?.Conclusion:Intranasal dexmedetomidine combination with inhalation sevoflurane is a effective sedative scheme for MRI in children with high sedation success rate,short sedative time,recovery time and can improve efficiency of clinical work.