"Regulate Spleen And Stomach Stitch" Or "Deep Stab Yang Stitch" Treatment Of Diabetic Nephropathy Ⅲ Period Clinical Research

Objective: Observe “the spleen and stomach stitch”or “deep stab Yang stitch”treatment of diabetic nephropathyⅢclinical curative effect and safety,and modern Chinese medicine treatment of the disease will provide new ideas and methods,improve the quality of health survival of patients,and provide new clinical support for the acupuncture treatment of the disease.Methods: A randomized group of 70 clinical subjects who were treated in the acupuncture clinic of the Affiliated hospital of tianjin institute of traditional Chinese medicine from March 2019 to December 2019,with 35 cases in each of the observation group and control group.Both groups were given basic western medicine treatment such as blood pressure reduction,glucose reduction and lipid regulation.The observation group was treated with the method of “conditioning the spleen and stomach acupuncture” and “deep acupuncture and yang acupuncture”,while the control group was treated with conventional acupuncture.The needle retention time in the two groups was 30 minutes,once a day,6 days a week,and there was a 1-day interval between the courses,a total of 8 courses.Fasting blood glucose(FPB),2 hours postprandial blood glucose(2h PPG),glycated hemoglobin(Hb A1c),β2 microglobulin(β2-MG),urine microalbumin(U-ALB),and 24-hour urine protein quantification(24h UPr)Is the main clinical observation index.The TCM symptom score scale is recorded before and after treatment,and the test results are analyzed by clinical statistical data.Results: A total of 70 patients with diabetic nephropathy stage III were included in this study,2 cases were lost,68 cases were actually studied,the loss rate was 2.85%,and the sample loss rate was in line with the plan.1.General situation analysis: There was no statistically significant difference between the two groups in gender,age,course of disease,FPG,2h PPG,Hb A1 c,β2-MG,U-ALB,24 h UPr,and TCM symptom scores(P>0.05).This shows that the two groups are comparable.2.Analysis of comprehensive curative effect: After the treatment course,the effective rate in the observation group was 88.24%,and the effective rate in the control group was 76.47%.After statistical analysis,the difference was significant(P<0.05).3.Comparison of relevant blood glucose indicators: after the 8th course of treatment,the comparison between the two groups of FPG,2h PPG,and Hb A1 c before and after treatment was very significant(P<0.01);the comparison between the two groups FPG,2h PPG,Hb A1 cgroup,The difference is significant(P<0.05).4.Comparison of related protein indicators: After the end of the 8th course of treatment,the differences between the two groups of U-ALB,24 h UPr,and β2-MG before and after treatment were very significant(P<0.01);The comparison between U-ALB,24 h UPr andβ2-MG groups was significant(P<0.05).5.Comparison of TCM symptom scores: After the eighth course of treatment,the two groups were compared in the TCM symptom score groups before and after treatment.The difference was statistically significant(P<0.05);The difference between the two groups was significant(P<0.01).Conclusion: Through this clinical trial study,it was found that the “Spleen and Stomach Acupuncture”combined with the “Deep Acupuncture and Nayang Acupuncture”in the treatment of diabetic nephropathy stage III has a significant clinical effect and is superior to other traditional acupuncture therapies.Improving the quality of daily life of patients is worthy of clinical promotion and application.