ObjectiveThe use of Shaoyao Gancao Decoction eye patch,purified water eye patch and rest these three methods to treat asthenopia,by analyzing the changes in visual function parameters and symptom scores before and after treatment,evaluate the clinical efficacy of Shaoyao Gancao Decoction eye patch treatment for asthenopia,with a view to provide a theoretical basis for the application of Shaoyao Gancao Decoction in the treatment of asthenopia.MethodA total of 90 volunteers with symptoms of asthenopia were screened for ophthalmology clinics,and the volunteers were randomly divided into Traditional Chinese medicine eye patch group,purified water eye patch group and rest group.The traditional Chinese medicine eye patch group was treated with Shaoyao Gancao Decoction eye patch for 20 minutes,the purified water eye patch group was treated with purified water eye patch for 20 minutes,and the rest group was asked to close eyes for20 minutes.Three groups of volunteers were evaluated for visual function and symptom score before and after treatment.Self-control and comparison between groups were performed before and after treatment.The three treatment methods were observed for amplitude of accommodation,Positive Relative Accommodation,Negative Relative Accommodation,Accommodation Response,Near Point of Convergence and symptoms of asthenopia.Results1.Baseline:There was no significant difference in gender composition,age distribution and refractive composition between the three groups(P>0.05),which was comparable.2.Visual function parameters(1)Right eye adjustment amplitude,binocular adjustment amplitude,positive relative regulation,and regulation response:There was no significant difference between the groups(P>0.05).There was significant difference between the two groups before and after treatment(P<0.05).(2)Left eye adjustment amplitude:There was no significant difference between the groups(P>0.05).There was significant difference between the traditional Chinese medicine eye stick group and the pure water eye stick group before and after treatment(P<0.05).Rest group There was no significant difference in the comparison between the groups(P>0.05).(3)Negative relative adjustment and close-up of the collection:There was no significant difference between the groups(P>0.05).There was no significant difference between the two groups before and after treatment(P>0.05).3.Visual fatigue symptom score(1)Total symptom score:There was a statistically significant difference between the groups(F=10.621,P<0.001).The differences between the groups before and after treatment were statistically significant,and the differences were significant(P<0.001).(2)Insufficient long-term view:The difference between the groups was statistically significant(x~2=6.499,P=0.039),and the difference was statistically significant before and after treatment(P<0.05).(3)Blurred vision,dry eyes and foreign body sensation:There was no significant difference between the groups(P>0.05).There was significant difference between the groups of traditional Chinese medicine eye sticks before and after treatment(P<0.05),pure water.There was no significant difference in the group between the eyes and the rest group(P>0.05).(4)Diplopia,eyelid pain:There were statistically significant differences between the groups(P<0.05).There was no significant difference between the two groups before and after treatment(P>0.05).(5)Eye swelling:The difference between the groups was statistically significant(x~2=3.360,P=0.046).There was significant difference between the traditional Chinese medicine eye stick group and the pure water eye stick group before and after treatment(P<0.05).There was no significant difference in the rest group(Z=-1.732,P=0.083).(6)Eye pain:There was no significant difference between the groups(x~2=3.324,P=0.190).There was no significant difference between the two groups before and after treatment(P>0.05).(7)Tears:There was a statistically significant difference between the groups(x~2=6.607,P=0.037).There was a statistically significant difference between the groups of traditional Chinese medicine eye sticks before and after treatment(Z=-2.126,P=0.033),pure water.There was no significant difference in the group between the eyes and the rest group(P>0.05).(8)Itchy eyes:There was no significant difference between the groups(P>0.05).There was significant difference in the pure water eye patch group before and after treatment(Z=-2.070,P=0.038).There was no significant difference between the group and the rest group(P>0.05).Conclusion1.The results of this study suggest that the eye patch of Shaoyao Gancao Decoction is effective in improving the AMP of right eye,left eye and double eyes,PRA,AR.2.It is better than pure water eye patch and rest in improving the symptoms of asthenopia.3.It is effective in improving the symptoms of long-term vision,eye swelling and tearing.It is effective in improving diplopia,dry eyes,itchy eyes,foreign body sensation and eyelid pain.4.Shaoyao Gancao Decoction has certain immediate effects on improving visual function parameters and symptoms of athenopia.Some are not obvious,which could be related to the volunteers are not enough.Later the volunteers increased,in order to provide a more reliable clinical basis for the treatment of asthenopia. |