| This paper is mainly divided into two parts.The first part is literature review:The literature review mainly includes the research progress of the risk factors of asthma,the understanding of the pathogenesis of asthma in Traditional Chinese medicine and the research progress of the correlation between theory Yun-Qi and the occurrence of asthma.Firstly,the risk factors related to asthma were summarized from the aspects of epidemiology,host and environmental factors.Secondly,the understanding of the etiology and pathogenesis of croup by ancient and modern physicians is summarized.Finally,this paper summarizes the research progress of the correlation between the theory of Yun-Qi and disease from the aspects of the correlation between the innate Yun-Qi time range,the characteristics of Yun-Qi at birth and the characteristics of Yun-Qi after birth and the occurrence of disease.The second part is clinical research:PurposeBy analyzing the distribution of five-element motions and six climatic factors at birth patients with bronchial asthma,this paper discusses the correlation and intensity between the individual’s innate endowment and the occurrence of asthma,so as to provide a new way of thinking for the clinical prevention and treatment of asthma.MethodIn this study,a retrospective case-control study was adopted.Patients with bronchial asthma in the outpatient and ward of the respiratory department of Dong Zhi Men hospital were selected as the case group,and non-asthmatic patients in the outpatient and ward of the respiratory department of Dong Zhi Men hospital were selected as the control group,and the two groups were matched 1:1 according to gender,origin and nationality.This study collected information through questionnaires(including general information,five-element motions and six climatic factors at birth,exposure to asthma risk factors,clinical manifestations and laboratory tests of asthma patients).Descriptive statistics,rank sum test,univariate and multivariate logistic regression analysis were used to study the correlation between the five-element motions and six climatic factors at birth and asthma in two groups of patients,and to explore whether the individual’s innate endowment is related to the occurrence of asthma and the correlation strength of related factors.Result1 General situationA total of 424 subjects were included in this study,including 170 males and 254 females.Among them,212 asthma patients were included in the case group,including 85 males and 127 females.For each case collected according to the matching conditions,a control case was selected from the non-asthmatic patients who visited the clinic at the same time,and a total of 212 controls were included,including 85 male non-asthmatic patients and 127 female non-asthmatic patients,and there was no statistical difference in gender distribution between the two groups.In the case group,the age ranged from 60 to 22 years,with an average age of 46.10 to 11.35 years.The age of the control group ranged from 60 to 23 years,with an average age of 45.36 to 10.36 years.By rank-sum test(P>0.05),there was no statistical difference in age distribution between the two groups.2 Risk factor analysis2.1 SuiYun and onset of asthmaThe largest number of asthmatics were born in the Metal-year(14.6%),and the smallest were born in the Fire-year(5.2%).The Metal-year(P=0.030<0.05)and the Earth-year(P=0.031<0.05)were statistically significant,suggesting that both were significantly positively correlated with the occurrence of asthma,that is,the Metal-year and the Earth-year might be risk factors for the occurrence of asthma.Those born in golden years had 2.066 times the risk of asthma in non-golden years.People born in the Metal-year had 2.102 times the risk of developing asthma in the non-Metal-year,and born in the Earth-year had 2.102 times the risk of developing asthma in the non-Earth-year.2.2 six climatic factors and onset of asthmaThe largest number of asthmatics were born in the Metal-Yangming of SiTian(21.7%),and the smallest were in the Wood-Jueyin(12.7%),while in the control group,the largest were in the Metal-Yangming(23.1%),the smallest were in the Water-Taiyang(12.7%),and there was no significant difference between the two groups.The largest number of asthmatics were born in the Metal-Yangming of ZhuQi(22.6%),and the smallest were in the Junhuo-shaoyin(13.2%),while in the control group,the largest were in the Metal-Yangming(19.3%),the smallest were in the Water-Taiyang(14.2%),and there was no significant difference between the two groups.The largest number of asthmatics were born in the Wood-Jueyin of KeQi(19.8%),and the smallest were in the Metal-Yangming(14.2%),while in the control group,the largest were in the Wood-Jueyin(20.3%),the smallest were in the Earth-Taiyin(14.2%),and there was no significant difference between the two groups.It is suggested that six qi may not be correlated with the occurrence of asthma.2.3 Kezhu-Jialin and onset of asthmaIn the case group,the largest number were born in the same of XiangDe(51.9%),and the smallest were in the Xianghuo adding Junhuo(2.8%),while in the control group,the largest were in the same of XiangDe(51.9%),the smallest were in the Junhuo adding Xianghuo(3.8%),and there was no significant difference between the two groups.It is suggested that Kezhu Jialin may not be correlated with the occurrence of asthma.2.4 YunQi-TongHua and onset of asthmaIn the case group,the largest number were born in the non YunQi-TongHua(44.3%),and the smallest were in the TaiYi-TianFu(2.8%),while in the control group,the largest were in the non YunQi-TongHua(47.2%),the smallest were in the SuiHui and TongTianFu(5.2%).The distribution of SuiHui and TongTianFu(P=0.030<0.05)in the case group and the control group was statistically significant.Those born in SuiHui and TongTianFu had 2.475 times the risk of asthma in non SuiHui and TongTianFu years,that is,SuiHui and TongTianFu years might be risk factors for the occurrence of asthma.2.5 YunQi-YiHua and onset of asthmaIn the case group,the largest number were born in the BuHe year(31.5%),and the smallest were in the TianFu year(8.9%),while in the control group,the largest were in the BuHe year(47.2%),the smallest were in the ShunHua(16.4%).The distribution of TianXing year(P=0.006<0.05)in the case group and the control group was statistically significant.Those born in TianXing year had 2.071 times the risk of asthma in non TianXing year,that is,the TianXing year might be risk factors for the occurrence of asthma.Conclusion(1)There was a certain correlation between the characteristics of innate endowment at birth and the incidence of asthma.(2)The Metal-year and the Earth-year of SuiYun might be the risk factors for the incidence of asthma.The SuiHui and TongTianFu and TianXing-year might be related to the incidence of asthma. |