Correlation Between Ultrasonographic Scoring System And Pathological Grading Of The Salivary Glands In Primary Sjogren’s Syndrome

Objective:To investigate the correlation and diagnosis value between ultrasonographic scoring system and pathological grading of the salivary glands in primary sjogren’s syndrome(PSS).Methods:Sixty-nine patients with a suspected diagnosis of PSS were included in the study.They were examined by ultrasonography and labial salivary gland biopsy.The ultrasound imagings of the salivary glands were analyzed and graded according to a 5-point(0-4)ultrasonographic scoring system.The results of labial salivary gland biopsy were graded according to the degree of lymphatic infiltration.The receiver operating curve(ROC)was drawn and the area under curve(AUC)was calculated to test the diagnostic performance of two methods.Spearman rank correlation analysis was used to compare the correlation between the two methods.Results:The sensitivity,specificity and AUC of the ultrasonographic scoring system were 87.0%、78.3%、0.882.The sensitivity,specificity and AUC of the salivary gland biopsy were 76.1%、87.0%、0.869.The ultrasonographic scoring system and pathological grading showed a significant positive correlation(r=0.714,P<0.01).Conclusion:There is a good consisitency between the ultrasonographic scoring system and pathological grading of the salivary glands.As the diagnostic value of two methods are similar,ultrasonography reaches great diagnostic efficiency in PSS.