Correlation Analysis Of Breastfeeding And Metabolic Syndrome In Female Population In Suburbs Of Hefei City

Objective: To explore the relationship between breastfeeding and the incidence and components of metabolic syndrome(MS)in female populations in the suburbs of Hefei.Methods: The research object comes from the database established by the research group in the "REACTION Study on the Risk of Tumors in Chinese Type 2 Diabetes Patients" in 2012,and selects Changqing Street,Baohe District,Hefei City,High-tech Zone Shunan Court,Haiheng Community and Jinxiu Community of the Economic Development Zone have a total of 4 suburban community populations,a total of 9986 permanent residents aged over 40(residence time ≥5 years)as the survey subjects,according to the exclusion criteria,a total of 6,250 populations were finally included in this analysis According to whether they were breastfeeding after childbirth,the subjects were divided into breastfeeding group and non-breastfeeding group,including 464non-breastfeeding group and 5786 breastfeeding group;Divided into four subgroups according to the duration of breastfeeding,namely ≤6,6～≤12 months,12～≤18months and ≥ 19 months groups.Comparing the baseline data of subjects between different groups,assessing the odds ratio(OR)(95% CI)of MS and its components based on the duration of feeding,using multiple logistic regression analysis to calculate OR to analyze breastfeeding and The relationship between its feeding time and MS and its components.Results:(1)Among the 6250 female populations surveyed in this group,464(7.4%)women were not breastfeeding,and there were 5786(92.6%)breastfeeding women.The overall prevalence of MS was 1371(21.9%),among which the number and prevalence of MS in the breastfeeding group and non-breastfeeding group were respectively 1234(21.3%)and 137(29.5%).(2)In the analysis of the baseline data of the four subgroups of the breastfeeding group,the detection rate levels of age,education level,LDL,SBP,BMI,and fasting blood glucose were different,which was statistically significant(P<0.01);among them,compared with the other feeding groups,≤ 6 months The ages in the group were all younger than the other groups.The SBP and LDL were the highest in the ≥19 months group,while the BMI and education were the lowest(P<0.01),and the fasting blood glucose was the lowest in the 12-18 months group(P<0.01);There was no statistical difference in WC,DBP,gestational hypertension and gestational diabetes,biochemical indicators(including HDL,CHOL,TG),number of pregnancy,number of abortions,number of surviving children,age at menopause(P>0.05).(3)After adjusting for potential confounding factors,including age,previous history of MS,alanine aminotransferase(ALT),aspartate aminotransferase(AST),glutamyl transpeptidase(GGT),number of pregnancies,number of miscarriages,number of surviving fetuses,For fetal sex,hypertension during pregnancy,and diabetes during pregnancy,taking the non-breastfeeding group as a reference,the prevalence of breastfeeding MS was reduced by 0.69 times(95% CI,0.59～0.98).In the breastfeeding group,taking the ≤6 months group as a reference,the risk of MS in the 6～≤12,12～≤18 months and ≥19 months group was significantly reduced,respectively 0.86 times(95%CI,0.76～1.09),0.75 times(95% CI,0.68～1.00)and 0.78 times(95% CI,0.65～0.97).(4)In the analysis of MS components,taking the non-breastfeeding group as a reference,the breastfeeding group will have increased blood pressure,increased blood lipids,increased blood sugar,and lowered the risk of obesity in the future,which were reduced by 0.98 times(95%CI: 0.94).～1.23,P=0.01),0.99 times(95%CI: 0.94～1.23,P=0.03),0.99 times(95%CI: 0.92～1.14,P=0.03)and 0.93 times(95%CI: 0.89～1.28),P = 0.01);among them,compared with the other feeding groups,the 12 to ≤ 18 months group had the lowest risk of blood pressure,blood lipids and obesity in the future,which were reduced by 0.90 times(95%CI: 0.70～1.18,P<0.05),0.89(95%CI: 0.69～1.12,P<0.05)and 0.70 times(95%CI: 0.53～0.92,P<0.05).≥19 months group had the lowest risk of blood glucose elevation in the future,which was reduced by 0.62 times(95%CI:0.52～0.86,P<0.05).Conclusion: Among women in the suburbs of Hefei,women who have not breastfed have an increased risk of developing metabolic syndrome in the future,and women who have been breastfeeding for 12 to 18 months can reduce their risk of MS in the future.