Correlation Between Lung Function And Body Mass Index,age And Education Level In Patients With Chronic Obstructive Pulmonary Disease In Cangzhou Area

Objective:To explore the relationship between BMI,age,education level and major indexes of lung function in COPD patients in Cangzhou area,and to explore the correlation between BMI and dyspnea grade in COPD patients.Methods:The data of pulmonary function FEV1,FEV1%,FEV1/FVC,age(years),gender,height(m),weight(kg),education level,dyspnea grade of COPD patients who met the diagnostic criteria were collected from March 2019 to July 2020 in Cangzhou"Happy Breathing"China COPD grading diagnosis and treatment project.BMI was divided into three groups:low BMI group(BMI<18.5kg/m~2),normal BMI group(18.5kg/m~2≤BMI<24kg/m~2)and high BMI group(BMI≥24kg/m~2).According to their age,they were divided into non-elderly group(age≤65years)and elderly group(age>65years).According to the level of education:1.Primary school and below 2.Junior high school 3.Senior high school 4.Technical secondary school and above.A modified version of the British Medical Research Council Respiratory Questionnaire(m MRC)was used to classify the degree of dyspnea in patients with COPD:Grade 0:Difficulty in breathing only during strenuous activities;Grade 1:Shortness of breath during fast walking on flat ground or walking on small slopes;Grade 2:Due to shortness of breath,walking on flat ground is slower than normal peers or needs to stop and rest.This article mainly explores the relationship between BMI,age,education level and main indicators of lung function in COPD patients in Cangzhou area,and explores the correlation between BMI and dyspnea classification.Results:1.The pulmonary function index,BMI,age,education level and dyspnea grade data of 569 patients with COPD were included in the study.The results indicated that BMI was positively correlated with FEV1%(correlation coefficient P=0.029,r=0.092),which was positively correlated with FEV1/FVC(P=0.004,r=0.119)and FEV1(P=0.003,r=0.126)of the patients.FEV1,FEV1%and FEV1/FVC in the low BMI group were statistically significant different from those in the normal BMI group and the high BMI group(P<0.05),while there were no statistically significant differences in FEV1,FEV1%and FEV1/FVC in the normal BMI group and the high BMI group(P>0.05).2.Age was negatively correlated with FEV1%of patients(correlation coefficient P=0.002,r=-0.108),and was negatively correlated with FEV1/FVC of patients(P<0.001,r=-0.152),and was negatively correlated with FEV1 of patients(P<0.001,r=-0.296).There was no significant difference in FEV1%between the elderly group and the non-elderly group(P>0.05).3.Education level was positively correlated with FEV1%(correlation coefficient P<0.001,r=0.159),and was positively correlated with FEV1/FVC of patients(P=0.016,r=0.101),and was positively correlated with FEV1 of patients(P<0.001,r=0.262).4.There was a negative correlation between dyspnea grade and BMI in COPD patients(correlation coefficient P<0.001,r=-0.159),and there were statistically significant differences in BMI among patients with different dyspnea grades(P<0.05).Conclusion:1.BMI of COPD patients in Cangzhou area was positively correlated with pulmonary function indexes and negatively correlated with dyspnea grade.Improving the nutritional status of patients would reduce dyspnea and other clinical symptoms and improve the prognosis.2.With the increase of age,the pulmonary function of COPD patients gradually decreased.3.Patients with higher education level of COPD have better indicators of lung function,and it is necessary to pay attention to standardized daily management guidance for patients with lower education level.