Analysis Of Different Risk Stratification And Related Factors Of Hospitalization Outcome In Patients With Acute Pulmonary Embolism

ObjectiveBy analyzing the relevant clinical data,blood routine,D-dimer,renal function indicators（urea,creatinine,uric acid）of patients with acute pulmonary embolism（APE）with different risk stratification and hospitalization outcomes,we can find out the clinical data of different risk stratification and hospitalization outcomes.To preliminarily judge the common clinical indicators of different risk stratification in patients with acute pulmonary embolism;to analyze the relevant factors affecting the hospitalization outcome of patients with acute pulmonary embolism,to provide help for the clinical diagnosis,treatment and long-term prognosis of acute pulmonary embolism.MethodsA retrospective analysis was made of patients with acute pulmonary embolism diagnosed in a tertiary hospital from June 2012 to June 2020,and 125 patients with acute pulmonary embolism who met the criteria were included as the research subjects,including 68 males and 57 females with an average age(68 ±14 years old,according to the relevant risk stratification in the Chinese Medical Association "Guidelines for Diagnosis,Treatment and Prevention of Pulmonary Thromboembolism 2018 Edition",patients with acute pulmonary embolism were divided into low-risk acute pulmonary embolism group（69 cases）,intermediate-risk acute pulmonary embolism group（69cases）group（45 cases）,high-risk acute pulmonary embolism group（11 cases）.According to the outcome of hospitalization,they were divided into survival group（121 cases）and death group（4 cases）.The clinical data（demographic characteristics,length of hospital stay,underlying diseases and risk factors,clinical manifestations）,blood routine,D-dimer,and renal function indexes（urea,creatinine,uric acid）on admission were compared among the groups.Results1.Age,white blood cell count,neutrophil count,neutrophil-to-lymphocyte ratio,D-dimer,urea,The levels of creatinine and uric acid in patients with lower risk acute pulmonary embolism were significantly increased,and there was a significant difference between the two groups,P<0.05,which was statistically significant.2.Compared with the patients with acute pulmonary embolism in the death group and the patients with acute pulmonary embolism in the survival group,the red blood cell count,hemoglobin and hematocrit of the patients with acute pulmonary embolism in the survival group were higher than those in the patients with acute pulmonary embolism in the death group.The red blood cell distribution width of the patients with acute pulmonary embolism in the death group was significantly higher than that in the patients with acute pulmonary embolism in the survival group,and there was a significant difference between the two groups,P<0.05,with statistical significance.3.Logistic multivariate binary regression showed that patients with intermediate-risk acute pulmonary embolism were more likely to have elevated NLR（P=0.029,OR=1.124,95%CI: 1.012-1.249）.The ROC curve of the NLR index was drawn,and the results showed that the NLR had a sensitivity of 75.6% and a specificity of 50.7% in predicting patients with intermediate-risk acute pulmonary embolism.The comprehensive judgment rate of the layer is the highest.volume＿up content＿copy share.Conclusions1.Age,white blood cell count,neutrophil count,neutrophil-to-lymphocyte ratio,D-dimer,urea,creatinine,uric acid is helpful in evaluating the condition of patients with low-and intermediate-risk acute pulmonary embolism,in which NLR can independently affect the risk stratification of low-and intermediate-risk acute pulmonary embolism.2.Red blood cell count,hemoglobin,hematocrit,and red blood cell distribution width can be used to assess the risk of in-hospital death in patients with acute pulmonary embolism.Appropriate treatment measures are taken early to improve patient outcomes.