| Objective: To observe the therapeutic effect of Xiaoshui Decoction on communicating hydrocephalus after spontaneous subarachnoid hemorrhage,to evaluate the effect and safety of Xiaoshui Decoction on improving the symptoms of neurological deficit,and to explore its mechanism.Method: Sixty patients with aSAH-CHP who met the inclusion criteria were divided into treatment group and control group according to the method of digital randomization.The patients in the treatment group were given Xiaoshui Decoction on the basis of Western medicine treatment,while the patients in the control group were only treated with Western medicine.After 6 courses of follow-up,the changes of TCM symptom score,NIHSS score,imaging Evans index,GOS score and related safety index were recorded and analyzed statistically.Result:After the clinical study,the scores of main symptoms,secondary symptoms and total symptoms(main symptoms plus secondary symptoms)in the treatment group were significantly lower than those in the control group,with statistical significance.There were significant differences between the two groups in the scores of main symptoms(p=0.013 > 0.05),and the scores of secondary symptoms and total scores were less than 0.01 after statistical test,with significant statistical difference.The effective rate of the treatment group was 83.3%,which was significantly higher than that of the control group(70.0%).The NIHSS score in the treatment group was significantly lower than that in the control group in terms of reducing the neurological deficit score,and the curative effect was significantly better than that in the control group(p=0.009<0.01).There were no significant differences in imaging manifestations,GOS scores and adverse reactions(P>0.05).Conclusion: Xiaoshui Decoction has definite therapeutic effect on aSAH-CHP,can improve the clinical symptoms of hydrocephalus,reduce NIHSS score,and has no obvious adverse reactions and side effects. |
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