| Objective:To sum up the rule and characteristics of the treatment of insomnia,sum up the common type and prescription of primary insomnia in old age,and observe the effectiveness and safety of Bupleurum with keel and oyster Decoction in the treatment of primary insomnia in old age(evil offender Shaoyang syndrome).Methods:The theoretical research summarizes the rules and characteristics of Zhongjing’s treatment of insomnia by studying 29 articles on Treatise on Febrile Diseases.Clinical collection of 500 cases of elderly primary insomnia patients,excluding incomplete data,using Spss22.0 statistics,using the inter-group distance method,according to 2-5 categories of clustering,clustering analysis of elderly primary insomnia often witnessed and prescription.Clinical collection of 120 patients with primary insomnia in the elderly,excluding those who did not meet the standards,were randomly divided into 58 cases of treatment group,and oral " Bupleurum with keel and oyster Decoction " was combined with Alprazolam tablets;Control group 58 cases,oral alprazolam tablets.The treatment course was 4 weeks.The SSRS score,PSQI score,and the changes of symptoms and signs of Chinese medicine before and after treatment were observed and analyzed.Results:Clinical observation and analysis after 4 weeks of medication: In terms of clinical efficacy,the total effective rate of control group and treatment group was 68.96 % and 96.55 % respectively.The clinical effect of treatment group was higher than that of control group(P<0.01).2.In terms of sleep conditions,the improvement of sleep conditions in the treatment group was significantly better than that of the control group(P<0.01).3.Compared with the self-assessment of sleep condition before and after treatment,the sleep condition of the treatment group was significantly better than that of the control group(P<0.01).4.In terms of TCM symptom points,the improvement of TCM symptoms in the treatment group was significantly better than that in the control group(P <0.01).5.There were no obvious adverse reactions in the two groups during the clinical study.Conclusion:By studying the 29 articles on insomnia in the "Treatise on Febrile Diseases",it is concluded that Zhong Jing’s law of differentiating and treating insomnia is attributed to the six meridians and mainly to heart,kidney and liver.Bupleurum with keel and oyster Decoction has obvious clinical effect on primary insomnia in the elderly with Shaoyang type of evil criminals and the improvement of TCM symptoms.It improves the sleep quality of patients and has no obvious adverse reaction. |