| ObjectiveIn this study,through the prospective control clinical experiment,observe the therapeutic effect of the experimental group(Tongyuan acupuncture group)and the control group(drug group)in the treatment of tumor related insomnia,compare the therapeutic effect difference between the two groups and the change of tumor necrosis factor(TNF),understand the characteristics of tumor related insomnia,seek a safe and efficient clinical treatment method,and enrich the treatment of the disease The treatment method can give patients more and better choice space,so as to expand the application scope of Tongyuan acupuncture.MethodIn strict accordance with the inclusion criteria,70 cases were randomly divided into Tongyuan acupuncture group(35 cases)and drug group(35 cases).Two groups were given basic sleep health guidance,and the corresponding treatment,a week for a course of treatment,a total of 4 courses of treatment.At the end of the course,the changes of Pittsburgh sleep quality index(PSQI)and tumor necrosis factor(TNF)were evaluated.Finally,the relevant statistical treatment and conclusions were drawn.Result1.Before treatment,there was no significant statistical difference in gender,age,disease type,stage and Pittsburgh sleep quality index between the two groups(P>0.05).The comparison between the two groups was comparable.2.Curative effect comparison:total effective rate:the total effective rate of Tongyuan acupuncture group was 85.29%,and that of drug group was 77.14%.The total effective rate of Tongyuan acupuncture group was higher than that of drug group,but there was no significant difference between the two groups by Fisher test(P>0.05).In terms of clinical efficacy,there were 4 cases(11.76%),25 cases(73.53%)and 5 cases(14.71%)in Tongyuan acupuncture group,2 cases(5.71%),25 cases(71.43%)and 8 cases(22.86%)in drug group.There were no cured cases in both groups.According to Mann Whitney U test,there was no statistical difference in clinical efficacy between the two groups(P>0.05),but the total effective rate,apparent efficiency and effective rate of the experimental group were higher than those of the control group,indicating that the Tongyuan acupuncture group was not inferior to the drug group.3.PSQI score comparison within the group:before and after treatment,the PSQI sleep quality,sleep time,sleep time,sleep efficiency,sleep disorders,hypnotics,daytime dysfunction scores in Tongyuan acupuncture group were significantly improved,and statistically significant differences were found(P<0.05).Before and after treatment,PSQI sleep quality,sleep time,sleep time,sleep disorders,hypnotic drugs,daytime dysfunction scores in drug group were significantly improved.Statistically,there was significant difference(P<0.05).Sleep efficiency score,statistically,there was no significant difference(P>0.05).It shows that Tongyuan acupuncture group and drug group can effectively improve tumor related insomnia And Tongyuan acupuncture group was not inferior to the drug group.4.PSQI score comparison between groups:in the PSQI scale of the two groups,there were significant differences in sleep quality,sleep time and sleep efficiency in Tongyuan acupuncture group after treatment(P<0.05);there were no significant differences in sleep time,sleep disorders,hypnotics and daytime dysfunction(P>0.05).It shows that the two groups can improve the sleep time,sleep disorders,hypnotics,daytime dysfunction,but the Tongyuan acupuncture group has better effect on sleep quality,sleep time,sleep efficiency than the drug group.5.Comparison of TNF:compared with the drug group,the level of TNF in Tongyuan acupuncture group before and after treatment was not statistically significant(P>0.05);compared with before treatment,the level of TNF in the two groups after treatment was not statistically significant(P>0.05).Conclusion1.From the statistical analysis of the overall effect,the score of Tongyuan acupuncture group and drug group in the treatment of tumor related insomnia can be improved.There is no significant difference in the overall effect,but the total effective rate,apparent efficiency and effective rate of Tongyuan acupuncture group are higher than those of drug group,so it is considered that Tongyuan acupuncture group is not inferior to the drug group.2.From the analysis of individual indexes,especially the analysis of sleep quality,sleep time and sleep efficiency,the therapeutic effect of Tongyuan acupuncture group is better than that of the drug group,which may be in accordance with the general pathogenesis of insomnia yin-yang imbalance under the guidance of the overall concept of traditional Chinese medicine,and play a role in the overall adjustment of human body,yin-yang,viscera,Qi and blood,spirit and Qi For use.In short,both of them are effective,but the sleep quality,sleep time and sleep efficiency of Tongyuan acupuncture group are better than those of the drug group,which is worth further promotion and research.3.The TNF level of the two groups could not be improved significantly. |