| Objective:To observe the clinical effect of modified Shoutai Wan on Early Threatened Abortion accompanied by choriohematoma,to explore its possible mechanism,and to enrich the TCM treatment of threatened abortion of ki dney deficiency and blood stasis type,so as to provide the clinical basis for the treatment of this disease.Methods:60 patients who met the inclusion criteria were randomly divided into two groups.The experimental group was treated with Chinese medicine Shoutai Wan and Western Medicine(progesterone injection+Dydrogesterone Tablets).The control group was treated with Gushen Antai wan and Western Medicine(progesterone injection+Dydrogesterone Tablets).After 14 days of treatment,the changes of TCM syndromes,the area of SCH,the area of SCH/gestational sac area,the changes of serum estradiol(E2),progesterone(P)and chorionic gonadotropin(β-hCG)before and after treatment,and the changes of serum glycogen-125(CA125)before and after treatment were observed in the two groupsResults:The effective rate of Shoutai Wan in the treatment of Early Threatened Abortion with choriohematoma was 93.33%.Before and after the treatment,there were significant differences in TCM syndrome score and CA125 value(P<0.01).There were significant differences in the area of SCH and the area of SCH/gestational sac area(P<0.05).After the treatment,there were significant differences in the area of SCH and the area of SCH/gestational sac area between the experimental group and the control group(P<0.01),there was significant difference(P<0.05)in TCM syndrome integral comparison and CA125 value comparison;there was no significant difference(P>0.05)in serum E2,P,β-hCG levels between the experimental group and the control group after treatment.Conclusion:The modified Shoutai Wan can effectively treat the early threatened abortion with chorionic hematoma,reduce the area of SCH,improve the symptoms of kidney deficiency and blood stasis,reduce the CA125 value,so as to improve the success rate of fetal protection. |
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