Clinical Study On The Age-related Factors Of Sudden Sensorineural Hearing Loss

Sudden deafness is a clinical common emergency of otolaryngology head and neck surgery,defined as: within 72 hours of sudden and unexplained sensorineural hearing loss,hearing loss in at least two adjacent frequency 20 DBHL and above.Sudden deafness is characterized by sudden hearing loss,tinnitus,and swelling of the ear.It can be accompanied by dizziness or dizziness.Due to the exact etiology and pathogenesis of sudden deafness,it is not clear that the therapeutic effect of sudden deafness is very different.With the increasing incidence of sudden deafness,a number of multicenter studies have been done at home and abroad,and a guide for clinical diagnosis and treatment has been published.These guidelines regulate clinical diagnosis and treatment,and promote further research and understanding of sudden deafness.In recent years,a prominent feature of sudden deafness is the increasing number of children.At the same time,with the aging of society,the proportion of sudden deafness increases.Clinical observation shows that age related problems are an important factor in the process of sudden deafness and diagnosis and treatment.The incidence and clinical manifestations of sudden deafness in different age groups have their own characteristics,so they should be paid enough attention in the treatment process.This study was to explore the role of age related factors on the pathogenesis of sudden deafness,the clinical characteristics and treatment of sudden deafness comparing different age groups as a result,in order to further enrich and deepen understanding of sudden deafness and for different age groups will provide reference for the diagnosis and treatment of sudden deafness.ObjectiveTo explore the role of age related factors in sudden deafness and compare the clinical characteristics and treatment results of sudden deafness in different age groups.MethodsFrom December 2016 to December 2017,the diagnosis and treatment procedures and results of patients with sudden deafness in different age groups in the first affiliated hospital of zhengzhou university were observed.During the study,222 cases of sudden deafness were treated with single ear.112 males and 110 females;Left ear 109 cases,113 cases in the right ear;The age range from 2 to 80 years old was divided into 42 cases of children group(age < 18 years old),152 cases of middle-aged adults(19 ～ 60 years old),and 28 cases of old age group(age > 60).The duration of the disease was no more than 7 days in 102 patients,83 in 7 ～ 21 days,and 37 cases in the course of BBB 0 21 days.All patients were treated with glucocorticoid and improved inner ear microcirculation.Prior to the onset of infection,the history of virus infection plus antiviral drugs;Determination of thrombolysis according to laboratory fibrinogen test results;It also treats systemic disease and accompanying symptoms.The incidence,clinical manifestations,adjoint symptoms,hearing loss and hearing loss of patients with sudden deafness in all age groups were compared.Results1.The triggers and comorbid illness: children series before the onset of sudden deafness history ratio was significantly higher than that of Qing Zhong Nian virus infection group and elderly group(P < 0.017),of which the influenza virus infection in 7 cases,16.7%(7/42);5 cases of mumps virus infection,accounting for 11.9%(5/42);1 case of encephalitis infection,accounting for 2.4%(1/42).The proportion of stress/fatigue before onset in the three age groups was also significant(P < 0.05),Compared with the young and middle-aged group and the elderly group,the children group 16.7%(7/42)was significantly higher.The prevalence of sudden deafness in the elderly patients with hypertension and diabetes was 53.6%(15/28),which was significantly higher than the other two groups(P < 0.05),and was mostly severe and extremely severe hearing loss,accounting for 93.3%(14/15).2.Clinical manifestation: the severity of hearing loss was the most severe in children with sudden deafness,and the proportion of severe hearing loss was 59.5%,significantly higher than that of the other two groups(P < 0.017).The characteristics of the type distribution of the auditory threshold curve were: the proportion of low-frequency descending type was the highest in the middle-aged group,accounting for 9.9%(P < 0.017).The proportion of high frequency descending type was the highest in the elderly group,accounting for 50.0%(P < 0.017).The proportion of total deafness was highest in children group,accounting for 59.5%(P < 0.017).There was no statistical difference in the distribution of flat curves in all age groups(P <0.05).Hearing loss accompanied by tinnitus and vertigo were mostly seen in middle-aged and elderly groups,with the lowest group(P < 0.017).The elderly group had the highest proportion of hearing loss in the lateral ear,which was 32.1%(P <0.017).3.Therapeutic effect: The recovery rate and total effective rate of all patients was 31.5% and 79.28%.The total effective rate of the children group was lower than that of the elderly group and the young and middle-aged group(P < 0.017).However,the recovery rate of the elderly group was lower than the other two group(P < 0.05).Conclusion1.The incidence of sudden deafness in children is related to viral infection and stress fatigue.Elderly patients are more likely to have systemic diseases such as high blood pressure and diabetes.2.The incidence of sudden deafness in children was severe,and the proportion of severe and profound was higher.The high frequency hearing loss in elderly patients is more common,and there is more loss of lateral hearing.3.The total effective rate of children sudden deafness is the lowest,and the elderly patients are more difficult to recover.