Study On 2450MHz Microwave Irradiation Of Pork Fat And Its Computer Simulation

With the development of science and technology and the changing needs of human beings,the traditional thermal ablation technology is far from enough to meet the needs of people due to their respective shortcomings in terms of efficacy and usage.Microwave ablation is a new ablation method which utilizes the biological thermal effect of microwave to heat biological tissue to a certain temperature and achieve effective treatment.In recent years,microwave ablation as a new type of thermal ablation with its high efficiency,fast heating rate,strong penetration,no secondary contamination and other unique advantages have received more and more attention,and it is widely used in the field of clinical ablation.Compared with in vivo thermotherapy,extracorporeal hyperthermia has been one of the research hotspots in recent years due to its convenient operation,little harm to the human body,and no side effects.As the core problem of microwave ablation,the distribution of temperature field in biological tissues has always been the focus of research.The determination of the distribution of temperature field in biological tissues and the accurate prediction of microwave dose are urgent problems to be solved in the application field of microwave ablation,which are of great significance for medical diagnosis and clinical treatment.In this paper,a microwave treatment apparatus with a frequency of 2450 MHz is used as a microwave transmitter,and pork adipose tissue is the research object.By controlling the two variables of irradiation time and irradiation power,the temperature distribution on the upper surface of the adipose tissue and the inside of the tissue is explored.The microscopic morphology of adipose tissue at different temperatures was recorded and observed through a fluorescence microscope.The temperature rise curves showed that the temperature rise of the upper surface of the adipose tissue decreased gradually with the increase of irradiation time when the irradiation power was the same.When the irradiation power was small and the irradiation time was too short,no heat-transfer depth was produced in the adipose tissue,and the heat-transfer depth began to appear only when the upper surface temperature was higher than 41.8℃,and the heat-transfer depth increased with the increase of irradiation time and irradiation power.At the same time,under the conditions of this experiment,when the irradiation power is 50 W and the irradiation time is 15 min,the microwave effect is the best,and the purpose of microwave ablation can be achieved without damaging the normal tissue.The simulation software COMSOL Multiphysics was used to numerically model the above experimental process,and the extracted simulation data were plotted by Origin drawing tool.When the depth exceeds 10 mm,the tissue temperature decreases sharply.When the irradiation power was 50 W and the irradiation time was 25 min,the maximum heat-transferring depth of the adipose tissue was higher than 20 mm,and the results were generally consistent with the experimental temperature curves,excluding the effects of environmental and experimental errors.This study combines experimental and COMSOL Multiphysics numerical simulation modeling,and compares the results of both investigations,which are mutually tested and supported,illustrating the feasibility and convenience of COMSOL simulation modeling in microwave ablation applications.This study not only provides a basis for the study of temperature field distribution in microwave ablation,control of microwave dose and related superficial skin thermal therapy,but also facilitates the application of COMSOL Multiphysics simulation software for the investigation of microwave ablation.