A Preliminary Study On Laboratory Diagnosis And Clinical Classification Of COVID-19 Patients

Objective By analyzing the clinical laboratory characteristics of 53COVID-19 patients in Wuhan NO.1 Hospital,the correlation among the basic condition,liver function,renal function,myocardial function and blood index of COVID-19 patients and clinical types was discussed.Method COVID-19 mild(8 cases),ordinary(35 cases)and severe or critical patients(10 cases)were collected in Wuhan No.1 Hospital in February 11,2020.The clinical data and laboratory results including name,age,gender,blood routine,C reaction protein,liver and kidney function,myocardial markers,myocardial enzymes and D-Dimer were collected and compared among 53 patients.Result There were statistically significant age differences among the three groups(P<0.05),showing a significant increase trend,and the proportion of male patients was higher than that of female patients.With the aggravation of the disease,the indexes of D-dimer,CRP,LDH,TNI and AST in the three groups were significantly increased with the severity of the disease.Other indexes,such as ALT,UREA,CREA,CK,CKMB,MYO,were significantly higher in severe and critical patients,while for those of mild and ordinary patients the change is not obvious.In addition,the number of LYM decreased significantly.Conclusion Age is a risk factor for patients with COVID-19.As the disease progresses,in addition to lung lesions,different degrees of inflammation,liver and kidney damage,and myocardial damage will occur.Moreover,the severity of the injury is related to the clinical classification.Mild and ordinary patients only begin to show damage trends in some indicators,while most of the indicators in severe and critical patients rise and directly cause substantial organ damage.Therefore,when treating COVID-19 patients,it is necessary to monitor all organs as soon as possible to find high-risk patients in time and give the optimal treatment plan.