Clinical Study On Treating Kidney Deficiency And Dampness-heat Syndrome Of Overactive Bladder By Bigui Shuoquan Formula Granules

ObjectiveThe goal of this study was to look into the clinical efficacy and security of Bi Biquan Granules in the treatment of patients with bladder hyperactivity in a randomised controlled trial,in order to summarize the academic thoughts and clinical experience of the tutor Professor Zhang Chunhe in the treatment of overactive bladder,thus provide a certain theoretical basis and clinical guidance for the better treatment of overactive bladder in clinic.MethodsIn this study,A total of 72 OAB patients with kidney deficiency and dampness-heat type were theorem of random with generate nonce by Excel.Including(experimental cluster and control cluster),the average allocation of 36 people in each group.The test group took Bigui Shuoquan Formula Granules,and the control group took Sanjin Tablets.Both of them took Solifenacin Succinate Tablets.After the course of treatment,the efficacy and safety of the treatment of Bigui Shuoquan Formula Granules were evaluated by comparing the overactive bladder questionnaire scores(OABSS),24-hour urination times,and TCM syndrome scores of the two groups before and after treatment.RelsultAmong them,the experimental group and the control group each contained 36 people.Due to different problems in the treatment of this subject,a total of 6 people were excluded,of which 3 cases were excluded in each group.Sixty-six participants were included in the study,with an average of 33 participants in each group.General data examination before treatment showed P>0.05,which was comparable.1.After treatment,the own OABSS of the two groups were overt lessen(P<0.05).After treatment,the unlike between the two clusters was statistically sinnvoll(P<0.05).2.Changes in OABSS after treatment with medication were compared between the two groups.Among them,the cure,remarkable effect,effective and ineffective of the experimental group corresponded to 5,15,11 and 2 respectively,0,10,20 and 3respectively,and the corresponding percentages were 15.2%,45.5%,33.3% and 6.0%,0.0%,30.3%,60.7% and 9.0%,and the whole valid of the group was 94.0%,91.0%.The ameliorate of OABSS score in experimental cluster was more sinnvoll than that in control cluster(P<0.05).3.After treatment,the own 24-hour emissions of urine count of the two groups were overt lessen(P<0.05).After treatment,the unlike between the two cluters was statistically sinnyoll(P<0.05).4.After treatment,the own TCM syndrome scores in both groups were significantly decreased,(P<0.05).After treatment,the unlike between the two clusters was statistically sinnvoll(P<0.05).5.Two cluters of patients after drug treatment,compared their TCM syndrome changes.In the experimental group,the clinical cure,remarkable effect,effective and ineffective cases were 7,13,10 and 3 cases respectively,2,8,20,and 3 cases respectively and the corresponding rates were 21.3%,39.4%,30.3% and 9.0% respectively,6.1%,24.2%,60.7%and 9.0%,respectively.The ameliorate of the ameliorate extent of TCM syndrome in experimental cluster was more sinnvoll than that in control cluster(P<0.05).6.No serious adverse reactions occurred in the two groups.ConclusionThe Bigui Shuoquan Formula Granules have a good curative effect on Kidney Deficiency and Dampness-heat Syndrome of Overactive Bladder,especially in improving OABSS,24-hour urination frequency,TCM syndrome score was sinnvoll better than the control cluster,and no owert untoward reactions.