| Objective: To investigate the clinical features of partially cellular leiomyoma and cellular leiomyoma by analyzing the clinical data of patients who underwent surgery in The Second Hospital of Jilin University and the pathological return to the uterine leiomyoma 、 partially cellular leiomyoma and cellular leiomyoma to help early diagnosis and make diagnosis and treatment more individualized.Research methods:We collected and collated the clinical data of patients who underwent surgery in The Second Hospital of Jilin University and the pathological return to the uterine leiomyoma 、 partially cellular leiomyoma and cellular leiomyoma from January 1,2016 to December 31,2019.Then the following basic information was recorded: admission time,admission number,name,age,surgical indications(including menstrual changes/abnormal uterine bleeding,hypogastralgia,abdominal mass,compression symptoms of abdominal mass,rapid growth of leiomyoma,etc.),pregnancy,delivery,results of preoperative color ultrasound examination,tumor size(maximum diameter),tumor location,number,postoperative pathology.Statistical software was used to analyze the clinical data of patients.Results:1.All the three groups of UL、PCL、CL had the most onset age in the 40-49 age group,and about 80% of the patients in the three groups had disease in the childbearing period(20-50 years old).2.UL 、 PCL 、 CL age distribution of the three groups accords with the normal distribution.The age trend of PCL is similar to that of CL.During childbearing age(20-50 years old),the incidence of UL 、 PCL 、 CL increased with age.After childbearing age(>50 years old),the incidence decreases with age.3.The difference of the average onset age between UL group and PCL group was statistically significant(P<0.05).The difference of the average onset age between UL group and CL group was statistically significant(P<0.05).There was no significant difference in average onset age between PCL group and CL group(P>0.05).4.The surgical indications were similar in the three groups of UL、PCL and CL,When surgical indications were menstrual changes/unusual uterine bleeding,lower abdominal pain,lower abdominal mass,and pelvic compression symptoms,there was no significant difference between the three groups(P>0.05).When the surgical indication was the rapid growth of leiomyoma during follow-up,the difference between UL group and PCL group was statistically significant(P<0.05),between UL group and CL group was statistically significant(P<0.05),the difference between PCL group and CL group was not statistically significant(P>0.05).5.There was no significant difference between the UL、PCL、CL three groups in ultrasonic echo performance(P>0.05).6.Menopausal differences between the three groups were statistically significant(P<0.05).The difference of menopause between UL group and PCL group was statistically significant(P<0.05),and the difference of menopause between UL group and CL group was statistically significant(P<0.05),and the difference of menopause between CL group and PCL group was statistically significant(P<0.05).7.There was no significant difference in history of gravidity and parity between the UL、PCL、CL three groups(P>0.05).8.There was no significant difference in the number of leiomyomas between the UL、PCL、CL three groups(P>0.05)..There was significant difference between the UL、PCL、CL three groups in the position of leiomyoma which includes subserosa、intramural myoma and submucosa(P<0.05).When the group of UL compared with the group of PCL:the incidence of subserous PCL was significantly higher than that of subserous UL,the difference was statistically significant(P<0.05);the incidence of intramural PCL was significantly less than that of intramural UL,the difference was statistically significant(P<0.05);there was no significant difference between the incidence of submucous PCL and that of submucous CL(P>0.05).When the group of UL compared with the group of CL:the incidence of subserous CL was significantly higher than that of subserous UL,the difference was statistically significant(P<0.05);the incidence of intramural CL was significantly less than that of intramural UL,the difference was statistically significant(P<0.05);the incidence of submucous CL was significantly higher than that of submucous UL,the difference was statistically significant(P<0.05).When the group of PCL compared with the group of CL:the incidence of subserous CL was significantly higher than that of subserous PCL,the difference was statistically significant(P<0.05);the incidence of intramural PCL was significantly higher than that of intramural CL,the difference was statistically significant(P<0.05);the incidence of submucous PCL was significantly less than that of submucous CL,the difference was statistically significant(P<0.05).10.The difference of diameter between the three groups of UL PCL and CL was statistically significant(P<0.05).When the diameter of leiomyoma is over 5cm,the difference of the prevalence of UL group and PCL group was statistically significant(P<0.05),there was no significant difference in the prevalence between the group of PCL and that of CL(P>0.05),and the same as the group of UL and that of CL(P>0.05).The difference of the incidence of the three groups of UL PCL CL was statistically significant when the leiomyoma diameter is over 10 cm(P<0.05).The difference of the incidence of the three groups of UL PCL CL was statistically significant when the leiomyoma diameter is over 15 cm(P<0.05).The difference of the incidence of the three groups of UL PCL CL was statistically significant when the leiomyoma diameter is over 20 cm(P<0.05).11.When compared about leiomyoma degeneration,there was significant difference between UL group and PCL group(P<0.05),and the same as significant difference between UL group and CL group(P<0.05).There was no significant difference between two groups of PCL and CL(P>0.05).Conclusion:1.The average onset age of PCL and CLwas less than the average age of UL,all mostly happened in women of childbearing age.2.When the surgical indication is the rapid growth of fibroids,the risk of PCL,CL is significantly increased.3.PCL ultrasound performance is mostly low-echo nodules,with no significant difference compared with UL,CL.4.The risk of CL、PCL in postmenopausal patients is higher,and the risk of CL is higher than that in PCL.5.When the location of fibroids is subserma membrane or intermuscle wall,the risk of PCL,CL is increased and the risk of CL is higher than that of PCL;When fibroids is submucosa,and the risk of CL is significantly higher than PCL,UL.6.Higher risk of PCL and CL with diameter greater than 10 cm,and CL is higher than PCL.7.PCL,CL is prone to pathological changes such as edema,glass,red and other pathological changes,but there was no significant difference between the two groups. |
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