The Clinical Effect Of Chaihu Shugan Powder Combined With Q-switched NdYAG1064nm Laser In The Treatment Of Chloasma With Stagnation Of Liver

Objective:Liver stagnation and qi stagnation are the main pathological factors in female patients with chloasma.In this research,Chaihu Shugan Powder combined with Q-switched NdYAG1064nm laser was used to treat patients with liver-stagnation and qi stagnation type chloasma.By observing the MASI score,TCM symptom score and the patient’s quality of life before and after treatment,it was hoped to explore the combination of Chaihu Shugan powder and Q The clinical effect of switching NdYAG1064nm laser in the treatment of patients with liver-stagnation and qi stagnation type chloasma..Methods:In this project,60 patients with melasma in the outpatient department of Dermatology of Jiangsu Provincial Hospital of traditional Chinese medicine from January 2020 to December 2020 were selected and randomly divided into the treatment group and the control group according to the treatment order,with 30 cases in each group.The treatment group was treated with Chaihu Shugan powder combined with Q-switched ndyag1064nm laser,while the control group was treated with Q-switched ndyag1064nm laser alone.The two groups were treated for 12 weeks.The melasma area and severity index score(Masi),TCM symptom score,skin disease quality of life index and clinical efficacy of the two groups were observed before and after treatment.Results:(1)At 6 and 12 weeks of treatment,the Masi scores of the two groups were significantly improved compared with those before treatment,and the difference was statistically significant(P<0.05).After 6 weeks and 12 weeks of treatment,the improvement of Masi score in the treatment group was better than that in the control group,and the difference was statistically significant(P<0.05).(2)After 6 and 12 weeks of treatment,the TCM symptom scores of the two groups were significantly improved compared with those before treatment,and the difference was statistically significant(P<0.05).The comparison between the two groups found that at 6 weeks and 12 weeks of treatment,the improvement of TCM symptom score in the treatment group was better than that in the control group,and the difference was statistically significant(P<0.05)(3)After 6 and 12 weeks of treatment,the scores of skin disease quality of life index in the two groups were significantly improved compared with those before treatment,and the difference was statistically significant(P<0.05).The comparison between the two groups showed that there was no significant difference in the score of skin disease quality of life index between the treatment group and the control group at 6 weeks of treatment(P>0.05),and the improvement of the two groups was similar.At 12 weeks of treatment,the improvement of the score of the treatment group was better than that of the control group,and the difference was statistically significant.(4)After 12 weeks of treatment,the total effective rate of the treatment group was 90%,and that of the control group was 80%.There was no significant difference between the two groups(P>0.05).Conclusions:In conclusion,Chaihu Shugan powder combined with Q-switched ndyag1064nm laser in the treatment of liver depression and qi stagnation type chloasma patients,the treatment results show that at the end of 12 weeks of treatment,Chaihu Shugan powder combined with Q-switched ndyag1064nm laser can significantly improve the patients’ Masi score,TCM symptom score and quality of life.After 12 weeks of treatment,the clinical total effective rate of the treatment group was 90%,and that of the control group was 80%.There was no significant difference between the two groups(P>0.05).Although this study has a certain effect on patients with liver-stagnation and qi stagnation type chloasma,this study also has certain shortcomings.First,the sample size of the study is relatively small.Although strict inclusion and exclusion criteria have been formulated,there are still certain options Secondly,the observation indicators are mostly subjective indicators,and there is measurement bias,which may affect the stability of the results;finally,the observation time for the efficacy is relatively short,and there is a lack of long-term clinical efficacy observation for patients with liver stagnation and qi stagnation.Therefore,it should be improved in future research.