| As a new type of two-dimensional material,MXenes material has the advantages of large specific surface area,high metal conductivity and abundant surface functional groups,which has recently aroused widespread interest.At present,the research of MXenes mainly focuses on titanium carbide and there is little research on titanium nitride（Ti2N）.Hence,this paper focuses on the preparation and characteristics of Ti2N.In this paper,Ti2N nanosheets were first prepared.Characterization utilizing electron microscopy etc.showed that the nanosheets had a single-layer or few-layer structure with small size and large specific surface area.On this basis,we then prepared gold-titanium nitride（Au-Ti2N）composite nanomaterials and focused on their SERS characteristics.The experimental results showed that the Au-Ti2N composite has a higher SERS enhancement than Au or Ti2N nanoparticles alone,and the detection limit for methylene blue（MB）is 100 p M.We discussed the SERS enhancing mechanism of Au-Ti2N composites from the aspects of electromagnetic field enhancement and chemical enhancement.The enhancing effect of the SERS composite structure also exists in Au@Ag and other noble metal nanoparticles,thus proving the potential application value of the metal-Ti2N composite structure as SERS substrates.In addition,this paper also proposes a dual-drug nano-carrier system based on Ti2N and silicone.The nano-carrier system targets breast cancer cells with Bombesin（BN）and loads drugs on the silicone.After incorporation into breast cancer cells,the silicone is hydrolyzed with the existance of glutathione,which triggers the release of the drug based on photothermal effects and acidic p H.Experiments showed that Ti2N has a large drug loading rate,good light-to-heat conversion efficiency,fine light-to-heat recycle stability,excellent photothermal and p H responses,etc.,which proves that the drug carrier system has good prospects in drug delivery and tumor treatment. |
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