Clinical Observation Of Thermosensitive Moxibustion On Primary Dysmenorrhea Of Cold Coagulation And Blood Stasis Type

Objectives:By observing and comparing the clinical efficacy of thermal moxibustion and ibuprofen extended-release capsule in the treatment of primary dysmenorrhea with cold clotting and blood stasis,we explore a more effective and comfortable solution for the treatment of primary dysmenorrhea with cold clotting and blood stasis,and provide some reference for the clinical treatment of primary dysmenorrhea with cold clotting and blood stasis.Methods:Sixty-six patients with primary dysmenorrhea of the cold-coagulation and blood stasis type who visited the Second People’s Hospital Affiliated to Fujian University of Chinese Medicine between June 2020 and September 2020 were selected and divided equally into two groups by a randomized trial design method.The test group was treated with thermal moxibustion(using Zhao’s thunder fire moxibustion strips as the moxibustion device),starting 5 days before menstruation,once daily,and stopping when menstruation came;the control group was treated with oral ibuprofen extended-release capsules,0.3g/time,twice daily,starting 3 days before menstruation,and stopping after the second day of menstruation.Both groups were treated for 5 consecutive days in each menstrual cycle,with 3 consecutive menstrual cycles as a complete course of treatment.The visual analogue score(VAS),TCM symptom score,dysmenorrhea symptom score and uterine artery pulsatility index,resistance index,systolic peak flow rate to diastolic peak flow rate ratio(S/D)were recorded before and after treatment,and the VAS and dysmenorrhea symptom score were followed up after 3 months of treatment.The data were statistically and analyzed using SPSS 22.0 software.Results:1.Baseline comparison: The general conditions such as age,age at menarche,duration of disease,menstrual cycle,degree of dysmenorrhea and the corresponding values of the observed indexes before treatment were compared between the two groups,and the differences were not statistically significant(P>0.05).2.Comparison of VAS: After treatment,VAS decreased significantly in both groups compared with pre-treatment,and the difference was statistically significant(P<0.01),and there was no statistically significant difference between the groups after treatment(P>0.05).There was a significant difference(P<0.01)in the test group and no significant difference(P>0.05)in the control group when compared with pre-treatment at follow-up.There was no significant difference(P>0.05)in the test group and a significant difference(P<0.01)in the control group when comparing at follow-up with post-treatment.The VAS of the test group at follow-up was lower than that of the control group,and the difference between the groups was statistically significant(P<0.01).3.Comparison of TCM evidence points: in the intra-group comparison,the points in both groups were lower after treatment than before treatment,and the difference was statistically significant(P<0.05).In the comparison between groups after treatment,the value of the test group was lower than that of the control group,and the difference was statistically significant(P<0.05).4.Comparison of dysmenorrhea symptom scores: In intra-group comparisons,both groups had lower scores after treatment than before treatment,with statistically significant differences(P<0.01).There was no statistically significant difference between groups after treatment(P>0.05).There was a significant difference(P<0.01)in the test group and no significant difference(P>0.05)in the control group when compared with pre-treatment at follow-up.There was a significant difference in the control group(P<0.01)and no significant difference in the test group(P>0.05)when comparing at follow-up with post-treatment.The scores of the test group at follow-up were lower than those of the control group,and the difference between the groups was statistically significant(P<0.01).5.Comparison of uterine artery hemodynamics: In intra-group comparison,the values of PI,RI and S/D of uterine artery were lower in both groups after treatment than before ipsilateral treatment,and the difference was statistically significant(P<0.05).After treatment,the PI,RI and S/D values in the test group were significantly lower than those in the control group,and the difference was statistically significant(P<0.05).6.Comparison of clinical efficacy: The recent total effective rate of the test group was90.00%,and the recent total effective rate of the control group was 83.87%,with no statistically significant difference(P>0.05).The total long-term effective rate of the test group was 86.67%,and the total long-term effective rate of the control group was 45.16%,with statistically significant differences(P<0.05).Conclusions:1.Both thermal moxibustion and ibuprofen extended-release capsules can effectively improve the clinical symptoms and uterine artery hemodynamics in patients with primary dysmenorrhea caused by cold clotting and blood stasis,and the former has better improvement on the TCM evidence score and uterine artery hemodynamics than the latter.2.The recent efficacy of thermal moxibustion and ibuprofen extended-release capsule in treating primary dysmenorrhea with cold clotting and blood stasis was comparable,but the long-term efficacy of the former was better than that of the latter,suggesting that the efficacy of the former was longer lasting.