| Objective: To sort out the medical records of inpatients with the first diagnosis of UA in the Department of Cardiology,Heilongjiang University of Traditional Chinese Medicine,to explore the characteristics of patients with this disease,the characteristics of TCM syndrome differentiation,the use of TCM,and related influencing factors.Prevention and treatment provide more valuable clinical references.Methods: Collected 269 inpatients who were first diagnosed with UA in the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine from December 2018 to December 2020.Statistics of age,gender,TCM tongue diagnosis and pulse diagnosis,TCM syndrome differentiation and use of TCM,TG and LDL-C measurement values,etc.,and the collected clinical medical records are sorted and analyzed.Result:1.Gender and age: This study included a total of 269 patients meeting the criteria,including 114 males(42.38%)and 155 females(57.62%).The minimum age is 42 years old,the maximum age is 89 years old,and the average age is 66.39±11.22 years old.There was no significant difference in the incidence of men and women in each age group.Grouped by age range,the incidence of women in the 40-year-old,50-year-old,60-year-old,70-year-old,and 80-year-old range were 4.83%,10.78%,17.10%,16.36%,and 8.55%;the incidence of men was 3.36%,respectively.10.40%,13.75%,10.41%,4.46%.2.Season of incidence and solar terms: The incidence of each season is spring(20.10%),summer(19.30%),autumn(20.40%),and winter(40.10%).The top five solar terms with the highest incidence rate are Daxue,Lidong,Qingming,Winter Solstice,and Light Snow.Four solar terms are located in winter and one solar term is located in spring.3.Triggers: Six types of triggers were counted in 269 patients: emotional agitation(2.60%),full meal(1.12%),fatigue(33.09%),cold and cold(2.60%),diarrhea(0.74%),and seizure without trigger(59.85%).4.Coronary heart disease history: among hospitalized patients,3.72%have a diagnosis of coronary heart disease with a history of t ≤ 1 week,25.54% with 1 week <t ≤ 1 year,35.69% with 1 year <t ≤ 5 years,and 5 years<t Those with ≤10 years accounted for 20.07%,those with 10 years <t≤20years accounted for 11.52%,and those with a medical history of t>20 years accounted for 4.46%.5.Tongue and pulse conditions:(1)Tongue quality: The top 4 tongue quality statistics of patients are purple dark tongue(123 cases),light tongue(87 cases),dark tongue(22 cases),and red tongue(15 cases).(2)Tongue coating: A total of 5 types of tongue coating were counted,mainly white greasy coating(129 cases)and yellow greasy coating(96 cases),greasy coating accounted for 83.65% of all tongue coatings.(3)Pulse condition: A total of 17 kinds of pulse conditions are counted,among which the pulse conditions of the first 8 digits of frequency are: Shen Shou pulse,Ru slow pulse,Xuan Shou pulse,Xuan Hua mai,Xuan Xi mai,Xuan mai,thin weak pulse,Hua mai.There were 52 cases of solid pulse type,15 cases of deficiency type pulse,and 202 cases of deficiency type and actual pulse type.6.Syndrome analysis and statistics of traditional Chinese medicine:Among the 10 syndrome types counted,the top three are 124 cases(46.10%)of heart and blood stasis,95 cases of phlegm-turbid obstruction(35.32%),and25 cases of phlegm and blood stasis(9.29%).7.The value and abnormal rate of triglycerides and low-density lipoprotein of phlegm-turbid obstructive type are higher than other syndrome types,P<0.01.8.Statistics on the frequency of use of traditional Chinese medicine: 162 of the 269 UA patients included oral Chinese medicine decoction,and the statistics of the three most common types of UA in this statistics are as follows:(1)For patients with phlegm-turbid obstructive obstruction,the total number of Chinese medicines was 209,and the frequency of the medicines totaled 798 times.The top 15 Chinese medicines were: Poria,Tangerine Peel,Licorice,Codonopsis,Angelica,Shenglonggu,Astragalus,Danshen,Gui Branches,White Peony,Scutellaria,Chuanxiong,Bupleurum,Fried Atractylodes,Qing Pinellia.(2)The CCP counts 171 traditional Chinese medicines for patients with heart-blood stasis,and the total frequency of the medicines is 650.The top 15 traditional Chinese medicines are: licorice,chuanxiong,angelica,Bupleurum,Poria,white peony,salvia,dangshen,peach kernel.,Tangerine peel,astragalus,rehmannia,red peony root,Ophiopogon japonicus,corydalis.(3)A total of 94 traditional Chinese medicines of phlegm and blood stasis are counted,and the frequency of drug use is 203 times.The top 15 traditional Chinese medicines are: Salvia Miltiorrhiza,Roasted Licorice,Poria,Codonopsis,Bupleurum,Tangerine Peel,Ophiopogon,Chuanxiong,Citrus aurantium,Alisma,Stir-fried Atractylodes,Trichosanthes,White Peony,Safflower,Red Peony.9.Chinese medicine cluster analysis: cluster analysis of 48 medicines with a frequency of use greater than 16%.The clustering results show that there are 10 groups of commonly used medicines for this disease and 8 types of commonly used medicine combinations.10.Statistics on the use of proprietary Chinese medicines: Statistics show that the most commonly used Chinese medicine injections for patients with unstable angina are Xingxiong Sodium Chloride Injection(32.34%),Salvia miltiorrhiza polyphenolate for injection(17.84%),and blood relief.Ning injection(15.24%),Guhong injection(14.13%),safflower yellow injection(13.11%).11.Comorbidities: 51.30% of patients with hypertension,16.73% with diabetes,39.41% with cerebrovascular disease,and 8.71% with hyperlipidemia.12.Western medicine usage: The usage rate of ACEI/ARB drugs accounted for 17.84%,the usage rate of β-blockers was 30.85%,the usage rate of Ca channel blockers was 32.71%,the usage rate of nitrates was 28.99%,and the usage rate of antiplatelet drugs was 37.17.%,lipid-lowering drugs32.17%.Conclusion:1.This study shows that after the age of 50,the prevalence of this disease has increased significantly,and the increasing trend of women is more obvious;the high incidence of UA is the spring and winter;the highest proportion of comorbidities is hypertension;more than half There is no obvious cause for the onset of UA patients,followed by fatigue.Antiplatelet drugs,Ca channel blockers,and lipid-lowering drugs are used more in UA patients.2.This study shows that the most commonly used Chinese medicine injections in hospitalized UA patients are Xingxiong Sodium Chloride Injection,Salvia Miltiorrhiza Polyphenolate for Injection,Shuxuening Injection,Guhong Injection,and Safflower Yellow Pigment injection.3.This study showed that the tongue quality of UA patients is mainly blood stasis,the tongue coating is mainly greasy coating,and the pulse is mainly composed of deficiency and excess pulse.The TCM syndromes of patients are mostly in three syndromes: blood stasis blocking the heart,phlegm turbidity obstruction,and phlegm stasis mutual accumulation.4.This study shows that the abnormal rate of TG and LDL-C of the phlegm-turbid obstructive type is higher than that of other syndrome types.5.According to the statistics of this study,the top eight Chinese medicines were used in order: Zhigancao,Ligusticum chuanxiong,Salvia miltiorrhiza,Bupleurum,Poria,Tangerine peel,Codonopsis,Radix Paeoniae Alba.6.Cluster analysis of traditional Chinese medicine: The clustering results show that there are 10 commonly used drug pairs and 8 commonly used drug combinations for this disease. |
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