Retrospective Analysis Of The Clinical Effect Of External Application Of Traditional Chinese Medicine On Children With Henoch Schonlein Purpura Abdominal Pain

ObjectiveObjective To retrospectively analyze the clinical effect of external application of Xiaohuang San or Jiawei Shuangbai San on abdominal pain in children with Henoch Schonlein purpura,including the improvement of the degree of abdominal pain and the shortening of the course of abdominal pain,and summarize the effect of external application of Xiaohuang San or Jiawei Shuangbai San on abdominal pain in children with Henoch Schonlein purpura,so as to provide reference for external application of traditional Chinese medicine in the treatment of abdominal pain in children with Henoch Schonlein purpura.MethodsThrough Jiahe electronic medical record system and Lianzhong digital medical record management system,the clinical data of children with Henoch Schonlein purpura who were diagnosed in the First Affiliated Hospital of Guangzhou University of traditional Chinese medicine from January 2018 to November 2020 and met the inclusion criteria were collected,such as gender,age,vital signs,clinical manifestations(including time and degree of abdominal pain),safety indicators and treatment methods Cases were analyzed retrospectively.According to whether to use Xiaohuang San or Jiawei Shuangbai San for external application to abdomen,the children who used Xiaohuang San for external application to abdomen on the basis of conventional treatment were divided into Xiaohuang San group,the children who used Jiawei Shuangbai San for external application to abdomen on the basis of conventional treatment were divided into Shuangbai San group,and the children who only used conventional treatment were divided into conventional treatment group.The degree and time of abdominal pain were compared among the three groups.ResultsIn this study,55 cases were collected,including 13 cases in the Xiaohuang San group,28 cases in the Shuangbai San group and 14 cases in the conventional treatment group.The total effective rate was 92.3% in the Xiaohuang San group,100.0% in the Shuangbai San group and 100.0% in the conventional treatment group.There was no significant difference among the three groups(P > 0.05).The average days of abdominal pain were 2.31(± 1.44)days in the Xiaohuang San group,2.00(± 1.05)days in the Shuangbai San group,and 2.79(± 0.80)days in the conventional treatment group(P < 0.05).There was significant difference between the three groups(P < 0.05).There was no significant difference between the two groups(P > 0.05),and there was no significant difference between the two groups(P > 0.05).The average degree of abdominal pain of each group during the treatment was lower than that of the previous day.There was significant difference in the degree of abdominal pain in each group(P < 0.05),and there was no interaction between the treatment days and the treatment group(P > 0.05).There was no significant difference in the degree of abdominal pain between the groups on each day during the treatment(P >0.05).ConclusionJiawei Shuangbai San can shorten the days of abdominal pain in children with Henoch Schonlein purpura.External application of Xiaohuang San on abdomen may shorten the days of abdominal pain in children with Henoch Schonlein purpura,but the effect is not significant.Xiaohuang San or Jiawei Shuangbai San had no significant effect on the total effective rate of abdominal pain improvement,and had no significant effect on the daily improvement trend of abdominal pain during the treatment.