Research On The Influencing Factors Of Vitamin D Level Of Pregnant Women And The Influence Of Vitamin D Level Of Pregnant Women On Pregnancy Outcomes

Objective:To analyze the level of vitamin D in pregnant women and its influencing factors and to explore the influence of vitamin D deficiency in pregnant women on common adverse pregnancy outcomes,providing evidence for the prevention and intervention of vitamin D deficiency in pregnant women.Methods:The basic data and serum samples of pregnant women in our hospital from January2019 to June 2020 were collected,and the 25-（OH）D level of the serum samples was detected.Then the vitamin D levels in this area and its influencing factors were analyzed,and the relationships between vitamin D levels and common adverse pregnancy outcomes in the pregnant women as well as the incidence of small-for-gestational-age newborns were analyzed.Results:The vitamin D deficiency rate,insufficiency rate and adequacy rate of pregnant women were 83.28%,15.36% and 1.36% respectively,with vast majority of the pregnant women in a state of vitamin D deficiency.Analysis of the influencing factors on the vitamin D level of pregnant women showed that “28 ≤ gestational week ≤ 32,summer and autumn,high school education and above,outdoor exercise time ≥ 10 hours per week,supplementation of vitamin D and trace elements during pregnancy” were protective factors of adequate vitamin D adequacy in pregnant women.Linear correlation analysis showed that the vitamin D level of pregnant women was highly positively correlated with temperature,the higher the temperature,the higher the vitamin D level（r=0.907,t=6.818,P＜0.001）.The level of vitamin D in pregnant women was related to the occurrence of spontaneous abortion and small-for-gestational age（SGA）,with the incidence of spontaneous abortion and SGA in the "vitamin D deficiency group" higher than those of other groups（P＜0.05）.Conclusion:The serum vitamin D level of pregnant women in this area is relatively low,which is affected by multiple factors such as gestational week,season,education level of pregnant women,weekly outdoor exercise time,vitamin D and trace element supplementation during pregnancy.Low vitamin D levels can increase the risk of spontaneous abortion and SGA in pregnant women,so relevant effective measures should be strengthened to improve the vitamin D status of pregnant women.