Study On The Distribution Characteristics Of Six Meridians And Prescriptions In Vascular Cognitive Impairment

Objective:Through the collection of six-meridian differentiation,Formula-Patterns differentiation and through clinical symptoms and signs,the characteristics of six-meridian differentiation and Formula-Patterns differentiation on the Vascular cognitive impairment disorder were studied,and the Formula-Patterns differentiation law of prescription for Vascular cognitive impairment disorder was preliminarily clarified,aiming to provide a reference path for clinical application of prescription for vascular cognitive disorder.Methods:To conform to the inclusion criteria of 141 patients with vascular cognitive impairment,past history generally four diagnostic information collected related information,firstly identify the six-meridian,then the Formula-Patterns,corresponding theresult using SPSS software for statistical analysis,study of Vascular cognitive impairment’s six-meridian differentiation and Formula-Patterns distribution characteristics,and to explore each of the six-meridian distribution and the relationship between age and gender.Results:1.The study of 141 VCI patients can be divided into 20 six-meridian differentiations,including four single disease type 32 cases,Taiyin disease is most common among them,19 cases,accounted for 13.5%,Jueyin disease accounted for 5.0%,Shaoyang disease in 5 cases,accounted for 3.5%,1 case,the disease accounted for 3.1%of single by the disease percentage accounted for 0.7%of all patients percentage not seen Yangming disease and Shaoyin disease.There were 109 cases with 16 syndromes.Shaoyang-yangming disease is most common among them,24 cases,accounted for 17.0%,followed by Taiyin disease syndrome(19 cases),accounted for 13.5%,Taiyang-taiyin diseases 18 cases,accounted for 12.8%,Shaoyang-yangming-taiyin disseasa,18 cases accounted for more than 12.8%,Taiyang-shaoyang-taiyin diseases 9 cases,accounted for 6.4%,Taiyang-Yangming-Taiyin disease 8 cases,accounted for 5.7%,Yangming-taiyin disease 7 cases,accounted for 5.0%,Shaoyang-Taiyin,Jueyin-taiyin Shaoyin-Taiyin disease 5 cases,accounted for 3.5%,the rest of the patterns less frequently,the percentage is less than 5.0%respectively.In single disease and combined disease,it is concluded that:the lunarTaiyin disease and joint disease(including Shaoyang-yangming-taiyin disease,Taiyang-taiyin disease,Taiyang-shaoyang-taiyin disease,)most,a total of 98 cases,accounting for 69.5%.followed by Yangming disease and joint disease(including Shaoyang-yangming disease and Shaoyang-yangming-taiyin disease)in 65 cases,accounting for 46.1%.Shaoyang disease and joint disease(including Shaoyang-yangming disease and Shaoyang-yangming-taiyin disease)64 cases,accounting for 45.4%.It can be seen that the disease of VCI is complicated,involving a wide range of six meridians,most of which are combined diseases,and simple single meridians are rare.2.Based on 20 formula-patterns,a total of 71 prescriptions were found,among which,bupleurum decoction(including Xiaochaihu decoction,Dachaihu decoction,Sini powder,Chaihuj ialonggumuli decoction,Chaihuguizhiganj iang decoction and their corresponding addition and subtraction formulations)accounted for a total of 68 cases,accounting for 48.2%.It was followed by Guizhifuling decoction and its combination prescription(31 cases,accounting for 22.0%),Dangguishaoyao decoction and its combination prescription(30 cases,accounting for 20.6%),and Fangjidihuang decoction and its combination prescription(13 cases,accounting for 9.2%).3.Among the 141 patients with VCI,67 had unilateral prescription and 74 had combined prescription.The ratio of unilateral prescription and combination prescription was nearly equal.In the case of polyectasis,the prescription was precise and accurate,and the single prescription covered multiple channels.4.According to the statistical analysis,there was no significant difference in the distribution of vascular cognitive impairment in different gender and age groups.The previous medical history also had no significant effect on the distribution of the six syndromes.conclusions:1.The syndrome differentiation of VCI six is mainly comorbidities,and there are primary and secondary,shaoyang-yangming comorbiosis is the most frequently witnessed type.The disease is complicated,with less occurrence of single menstrual disease,no yangming disease and shaoyin disease,which may be caused by the small sample size and complicated disease of VCI itself.2.The pathogenesis of VCI is mainly qi stagnation,blood stasis,phlegm drinking and blood deficiency,and its symptoms are closely related to the mental illness in "treatise on typhoid and miscellaneous diseases",which is applicable to the multiple evidences of mental illness.3.VCI prescription is different,mainly bupleurum,chaihu and longgumuli prescription is the most common.The prescription of fangjidihuangtang,chaihu and The prescription of longgumuli prescription,The prescription of chaihuguizhiganj iang,The prescription of dachaihu,The prescription of xiaochaihu,The prescription of guizhifuling pill and the prescription of danggui shaoyao powder are the common prescription of treating VCI.