Clinical Observation Of Modified Wenfei Huayu Granules In The Treatment Of Children With UACS (cold Drink Over The Lung Type)

PurposeIn terms of theory,through the relevant literature review,to understand the current research progress of Chinese and Western medicine diagnosis and treatment of upper airway cough syndrome;in the clinical aspect,through observation on the treatment of phlegm-drinking pulmonary upper airway cough syndrome in children with Jiawei Wenfei Huayu Granules To verify the clinical efficacy of Jiawei Wenfei Huayu Granules in the treatment of this disease;and by testing the blood routine,interleukin-6 and immune function of children before and after treatment,observe the effect of Jiawei Wenfei Huayu Granules on the detection The influence of indicators,preliminary exploration of its possible mechanism,expands the treatment ideas for the clinical treatment of upper airway cough syndrome in children,and further clarifies the advantages of traditional Chinese medicine in the treatment of upper airway cough in children.MethodIn this study,children with cold drink pulmonary upper airway cough syndrome who met the inclusion criteria were divided into treatment group and control group.Among them,there were 27 cases in the treatment group and 22 cases in the control group,totaling 49 cases.The clinical data of 49 cases were collected..The treatment group was given Jiawei Wenfeihuayu Granules orally,and the control group was given budesonide suspension nebulized inhalation treatment,Patients with nasal symptoms in the two groups were treated with nasal irrigation.Before treatment,1 week of treatment,and 2 weeks after treatment,the syndrome score statistics were performed respectively,and the blood routine,interleukin 6,and immune function of the treatment group were tested before and after treatment.The observation results are statistically analyzed,combined with the improvement of syndromes and changes in index detection levels to comprehensively evaluate the clinical efficacy.Result1 Comparison results of disease efficacyAfter 3 weeks of treatment,in the total symptom score,the cure rate of the treatment group(74.1%)was higher than the control group(45.5%),and the effective rate of the treatment group(96.3%)was higher than that of the control group(68.2%).In the main symptoms,the cure rate(77.8%)in the treatment group was higher than that of the control group(36.4%),and the effective rate in the treatment group(92.6%)was higher than the effective rate in the control group(59.1%).In terms of secondary symptom scores,the cure rate(85.2%)of the treatment group was higher than that of the control group(59.1%),and the effective rate(100%)of the treatment group was higher than that of the control group(86.4%).The above comparison is statistically different(p<0.05).2 Comparison result of symptom scoreComparing within the group,after 1 week of treatment,the main symptoms of the treatment group(cough degree,cough frequency,sputum volume)scores,nasal symptoms(nasal congestion,runny nose,sneezing,nose)Itching)points,pharyngeal symptoms(dry throat,itchy throat,sore throat)points,other secondary symptoms(headaches,snoring)points,throat signs(pharyngeal congestion,posterior pharynx follicles)points scores were improved(p<0.05),the control group’s main symptoms score(cough degree,cough frequency,sputum volume),nasal symptom score(nasal congestion,runny nose,sneezing,nasal itching)),pharynx(dry throat,itchy throat,sore throat)symptom score,headache,snoring score,throat signs(pharyngeal congestion,posterior pharynx follicle)score were improved(p<0.05),suggesting that both groups can improve the symptom scores of children with cold-drinking pulmonary UACS.In the second week of treatment,the treatment group was concerned about the degree of cough,cough frequency,sputum volume,nasal congestion,runny nose,sneezing,nasal itching,dry throat,itchy throat,posterior pharynx follicles scores were improved(p<0.05),and the scores of the control group for nasal congestion,runny nose,sneezing were improved(p<0.05).At the 3rd week of treatment,the treatment group improved the scores of cough degree,cough frequency,nasal congestion,runny nose,sneezing,nasal itching(p<0.05).The control group improved the scores of sputum volume,runny nose,sneezing(p<0.05).After comparing between groups,after 1 week of treatment,the two groups had scores on the main symptoms(degree of cough,frequency of cough,sputum volume),scores of nasal symptoms(stuffy nose,runny nose,sneezing,nasal itching),pharynx(dry throat,Itchy throat,sore throat,symptom score,headache,snoring score,throat signs(pharyngeal congestion,posterior pharynx follicle)score Statistical difference(p>0.05).After 2 weeks of treatment,the two groups had differences in sputum volume,dry throat,pharyngeal congestion,and the treatment group was better than the control group.After 3 weeks of treatment,the two groups had statistical differences in the degree of cough,cough frequency,sputum volume,nasal congestion,sneezing,nasal itching,dry throat,itchy throat,headache.The group is better than the control group.3 Laboratory indicatorsIn terms of neutrophil/lymphocyte ratio(NLR),interleukin 6(IL-6),and IgE levels,there were significant differences before and after treatment(p<0.05),and the levels of NLR,IL-6,and IgE decreased after treatment.ConclusionJiawei Wenfei Huayu Granules are more effective than budesonide atomization treatment in improving the symptoms of children with cold drinking and pulmonary upper airway cough syndrome.The efficacy of the two groups was improved at the first week of treatment,but there was no significant difference in the efficacy of the two groups;the improvement of symptoms in the treatment group was better than that of the control group at the second and third weeks.The superiority of Jiawei Wenfeihuayu Granules Appears over time.By comparing the laboratory indicators of the treatment group before and after treatment,Jiawei Wenfei Huayu Granules may be able to reduce the neutrophil/lymphocyte ratio(NLR),interleukin 6(IL-6),and IgE of cold-yin-fus lung-type UACS Level.This topic shows the advantages of TCM in treating upper airway cough syndrome based on syndrome differentiation,embodies the idea of treating different diseases at the same time in TCM,and explores the possible mechanism of action of Jiawei Wenfei Huayu Granules in the treatment of upper airway cough syndrome,and will be useful for the future treatment of cold Drinking lung syndrome upper airway cough syndrome provides evidence and expands treatment ideas.