Analysis Of The Medication Rules Of Traditional Chinese Medicine In The Treatment Of Diabetic Gastroparesis Based On Literature Research

Research purpose: In this study,by searching the Chinese Journal Database,we collected the relevant literature on the treatment of diabetic gastroparesis with traditional Chinese medicine in the past ten years,and used data mining methods to sort out and analyze the medication rules of traditional Chinese medicine in the treatment of this disease,in order to provide a theoretical basis for the future clinical diagnosis and treatment of DGP,and provide a useful reference for the scientific research of traditional Chinese medicine.Research methods: Using CBM,CNKI,Wanfang and Weipu databases as search tools and literature sources,we collected all the papers on the effective treatment of DGP by traditional Chinese medicine from January 1,2010 to December 31,2019,and use Microsoft Office Excel Software to establish a database.We count the flavor,meridian tropism and drug classification of all traditional Chinese medicine and use frequency,frequency method to analyze high-frequencys.Taking single traditional Chinese medicine as the variable,all the traditional Chinese medicine appeared in the compound were assigned to 1,and those not appeared were assigned to 0.SPSS 24.0 was used to cluster analysis of high-frequency drugs to explore the law and significance of drug compatibility in the treatment of this disease.Research results: In this study,a total of 256 literatures were screened,involving 156 traditional Chinese medicines,with a total frequency of 2791 times.There are 23 flavors of commonly used Chinese medicine(frequency> 40 times),with a cumulative frequency of1869 times,accounting for 66.97% of the total frequency.It is the commonly used drugs for the treatment of DGP in the past ten years.In the aspect of medicine flavor: warm medicine takes the first place,followed by mild medicine and cold medicine,and the proportion of them is similar;sweet medicine takes the first place,spicy medicine takes the second place,and bitter medicine takes the third place.In the aspect of medicine meridian tropism :drugs entering spleen and stomach channels accounted for 27.56% and 19.21% respectively,followed by drugs entering lung channels,with a frequency of 16.16%.In terms of drug classification: the frequency of more than 200 times were tonic drugs,Qi regulating drugs,Xiaoshi drugs,phlegm resolving drugs and dampness resolving drugs,among which the tonic drugs,Qi regulating drugs and Xiaoshi drugs were the most,with a total frequency of 53.16%;in addition,among the tonic drugs with the highest frequency,Qi tonic drugs accounted for80.96% of the frequency.Conclusion:1.The core drugs for DGP are Atractylodes macrocephala,Pinellia ternata,licorice,Poria cocos,tangerine peel,Codonopsis pilosula and other 23 kinds of traditional Chinese medicine,of which Atractylodes macrocephala is the most frequently used drug.2.The drugs for DGP are mainly warm,sweet and entering the spleen and stomach meridian.3.The drugs for DGP are mainly tonifying drugs and regulating qi drugs.Among them,Qi tonifying drugs are the most important.4.Seven clustering results were obtained by cluster analysis.Xiangsha Liujunzi Decoction,Chaihu Shugan powder,Banxia Xiexin Decoction and Ziyin Jiangwei Decoction were the main prescriptions for diabetic gastroparesis.In clinical diagnosis and treatment of this disease,we can add and subtract syndrome differentiation on the basis of this: those with obvious food stagnation should be combined with Sanxian and Zhishi;If qi stagnation is obvious,it should be combined with Fructus aurantii and betel nut;If the nausea is obvious,it should be combined with ginger and Inula.