Study On The Preparation Of Bimetallic Oxygenates Composite Electrode And Their Application As Glucose Sensors

Diabetes can cause serious health problems and pose a threat to human health,and the detection and diagnosis of diabetes requires the use of glucose sensors.Glucose sensors are divided into two categories:enzymatic glucose（EG）sensors and non-enzyme glucose（NEG）sensors.EG sensors is significantly affected by environmental conditions such as p H,temperature,toxic chemicals and humidity.NEG sensors have attracted a lot of attention in recent years because of their advantages of fast and accurate response,low cost,and excellent sensitivity.At present,the materials used for NEG sensors,precious metals and their alloys are expensive,monometals and their oxides have low electrochemical activity,so there is an urgent need to develop a cheap,stable and sensitive NEG sensor material.In this paper,the bimetallic oxide compounds are loaded on the surface of carbon cloth（CC）by hydrothermal method,and the NEG sensor is constructed.The NEG sensing performance is improved by optimizing the conductivity of the material itself,controlling the micromorphology,and optimizing the test parameters.The specific content and conclusions are as follows:（1）NiCo₂S₄ with a square nanosheet-like structure is directly obtained by hydrothermal reaction.The nanosheets are about 1μm long and 0.5μm wide,closely connected to each other,and NiCo₂S₄ has a large specific surface area and porous structure.The prepared NEG sensor material can detect glucose with high sensitivity(971.42μA·m M^-1·cm^-2)and lower detection limit（2.3μM at 3 signal-to-noise ratio）.There is a linear relationship between glucose concentration and oxidation current（1μM-4.2 m M）.By detecting glucose for ten consecutive days,the current response of the test on the tenth day was 76.5%of the initial one,indicating that the sensor had good stability.The addition of different interfering substances such as ascorbic acid,uric acid,fructose and sucrose showed a high degree of selectivity.With the continuous addition of a single concentration of glucose,the resulting current response exhibits excellent stability and fast responsiveness.（2）Hydrothermal method and annealing treatment to prepare Co₂NiO₄@CC composite electrode materials with fine nanoneedle-like structure.The nanoneedle is about 3μm long,about 20 nm in diameter,and the hole diameter is concentrated at about 9 nm.When testing NEG sensor performance,the Co₂NiO₄@CC material exhibits high sensitivity of 29.72μA·m M^-1·cm^-2,a wider linearity range of 1μM-11.5 m M,and a lower detection limit（1.65μM）at a signal-to-noise ratio of 3.Continuous sensing 10times retains 80.1%of the response current.NEG sensors constructed of nanocomposites have high sensitivity,excellent interference immunity,extremely low detection limits,and good stability.Based on Co₂NiO₄@CC and NiCo₂S₄@CC,the two NEG sensor materials have excellent sensing performance and provide new research ideas for high-efficiency NEG sensor materials.