Effect Of Essential Hypertension On Nonvalvular Atrial Fibrillation

Purpose:In this topic,by studying the effect of elevated SBP(simple elevated SBP,simple DBP)on the occurrence of AF,we explore elevated SBP and increased DBP,which is more related with the occurrence of AF.It provides a more accurate evidence for clinical prevention in patients with hypertension combined with AF,thereby reducing the incidence of AF and the health and economic burden caused by related treatments.Methods:Patients treated at the Affiliated Hospital of Inner Mongolia University for Nationalities and the Inner Mongolia Forestry General Hospital from December 2019 to December 2021 were collected retrospective.First,we screened the patients with primary hypertension,Then,Patients with primary hypertension were screened and classified into primary hypertension and primary hypertension was combined with atrial fibrillation groups based on whether the diagnosis of AF was made.By collecting relevant data(age,gender,BMI,smoking history,alcohol consumption history)and hypertension typing(systolic and diastolic BP alone)for analysis.By using the comparison of the two groups were used to determine whether the occurrence of AF alone was associated with elevated systolic BP and elevated diastolic BP.And how does AF correlated to the two.The hypertension group was further divided into two groups according to hypertension levels1,2,and 3 to explore the relationship between the occurrence of AF and the baseline levels of hypertension.Results:The proportion of increased systolic hypertension and diastolic BP alone in primary hypertension and atrial fibrillation were all higher than those of primary hypertension,and the difference was statistically significant(p<0.05).Then,A binary logistic regression model was established by using whether atrial fibrillation was combined as the dependent variable,and with SBP alone and DBP alone as the independent variables,showed that Higher SBP alone is a risk factor for atrial fibrillation(OR=1.99,95%CI:1.20-3.28)and when corrected for age,gender,BMI,smoking history,and drinking history,increased SBP alone remains a risk factor affecting the occurrence of atrial fibrillation(OR=1.92,95%CI:1.15-3.19).Increased DBP alone is also a risk factor for atrial fibrillation(OR=1.85,95%CI:1.06-3.25).When corrected for age,gender,BMI,smoking history,and drinking history,increased DBP alone remains a risk factor affecting the occurrence of atrial fibrillation(OR=1.80,95%CI:1.03-3.13).There was no significant difference between sex,age,body mass index(BMI),smoking history,and alcohol consumption history(p> 0.05).The 127 patients with primary hypertension and atrial fibrillation were 28 in grade 1 hypertension,22%,35 in grade 2,27.6% and 64 in grade 3,50.4%.The 151 patients with primary hypertension included were divided into 47 in grade 1,31.1%,47 in grade 2,31.1%,and57 in grade 3,37.7%.There was no statistically significant difference in the distribution of hypertension in grades 1,2,and 3 between the two groups(p> 0.05).Conclusion:1.Elevated systolic BP and diastolic BP alone are all adverse factors that hypertension affecting atrial fibrillation.2.Elevated systolic BP alone may have greater effecst on AF development than elevated diastolic BP alone.3.Hypertension was typed at grades 1,2 and 3,and different levels of hypertension were not statistically significant incidence of AF.