| Objective:To explore the therapeutic effect of Chaihu Guizhi Tang combined with dapoxetine hydrochloride on secondary premature ejaculation of Ganqi Yujie type through clinical observation,in order to provide a reference for the clinical treatment of premature ejaculation.Methods:In the order of visiting time,the research data of 80 cases of Andrology Clinic,The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine(TCM)who met the standard of this subject were collected and randomly divided into treatment groups(Chaihu Guizhi Tang + hydrochloric acid for Poxetine)and control group(dapoxetine hydrochloride),40 cases in each group.A total of 73 cases were finally completed,including 36 cases in the control group and 37 cases in the treatment group.There were 7 patients who dropped out or discontinued the study due to personal reasons or lost follow-up,including3 in the treatment group and 4 in the control group.The treatment cycle was 8 weeks,and all patients participating in the study recorded age,disease course,IELT,PEDT score,TCM syndrome score,SAS score.Finally,all the data were summarized,sorted and compared and analyzed to judge the treatment effect.Results:1.There was no significant difference in age and course of disease between the two groups of research data(P>0.05),which can be used for clinical observation and research.2.IELT: The IELT of the control group before and after treatment were 136.78±19.36 s,217.31±67.16 s,respectively,and the IELT of the treatment group before and after treatment were 141.76±20.69 s,264.59±82.35 s,respectively.Before treatment,there was no significant difference in IELT between the two groups(P>0.05);after treatment,IELT was prolonged in both groups,and the prolonged time in the treatment group was greater than that in the control group,with statistical significance(P<0.05).3.PEDT score: The PEDT score of the control group before and after treatment was 14.64±1.88,12.72±2.90,and the PEDT score of the treatment group was 15.19±1.76,10.84±4.34 before and after treatment.Before treatment,there was no significant difference in PEDT scores between the two groups(P>0.05);after treatment,the PEDT scores of both groups were decreased,and the degree of reduction in the treatment group was greater than that in the control group,with statistical significance(P<0.05).4.TCM syndrome score: the TCM syndrome score of the control group before and after treatment was 11.94±1.85,7.22±2.27,and the TCM syndrome score of the treatment group was 12.67±1.97,5.92±2.98 before and after treatment.Before treatment,there was no significant difference in the scores of TCM syndromes between the two groups(P>0.05);after treatment,the scores of TCM syndromes in both groups decreased,and the degree of decrease in the treatment group was higher than that in the control group,with statistical significance(P<0.05).5.SAS score: The SAS score of the control group before and after treatment was 61.42±3.50,55.24±4.63,and the SAS score of the treatment group was 62.80±3.18,51.45±3.76 before and after treatment.Before treatment,there was no significant difference in SAS scores between the two groups(P>0.05);after treatment,the SAS scores of both groups decreased,and the degree of decrease in the treatment group was higher than that in the control group,with statistical significance(P<0.05).6.Statistics on the effective rate of the two groups: the total number of the control group was 36,the effective number was 20,the ineffective number was 16,and the effective rate was 55.56%;the total number of the treatment group was 37,the effective number was 29,and the ineffective number was 8,and the effective rate was 78.38 %;P<0.05,the difference was statistically significant.Conclusion:Chaihu Guizhi Tang combined with dapoxetine hydrochloride has a certain therapeutic effect on secondary premature ejaculation of Ganqi Yujie type,can prolong the patient’s IELT,improve the patient’s ejaculation control ability,reduce the PEDT score and the TCM syndrome score,and can improve the patient’s anxiety state. |
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