The Study On The Relationship Between Obstructive Sleep Apnea Hypopnea Syndrome And Depression

Objective:This subject is based on the theory of TCM mental disorder differentiation and treatment system,and makes a statistical analysis through the depression and discomfort scale score and polysomnography(polysomnography,PSG)data.To study the correlation between the total score of the scale and sleep apnea hypopnea index(AHI),minimum oxygen saturation(LSaO2)and oxygen reduction index(ODI),and to explore the distribution of five factors(depression,qi stagnation,qi stagnation of trunk and limbs,sleep disorder and mental injury).Provide objective and effective measurement tools for clinical diagnosis and treatment of patients with obstructive sleep apnea hypopnea syndrome(OSAHS)from the psychological level,so as to accurately guide syndrome differentiation and provide new ideas and methods for clinical treatment of patients with obstructive sleep apnea hypopnea syndrome.Methods:In this study,101 patients with depressed sleep apnea hypopnea syndrome were selected from Shandong Hospital of traditional Chinese Medicine from August 2020 to December 2021.93 patients who met the inclusion criteria were divided into mild,moderate and severe cases according to AHI index.Poly somno graphy and depression scale score were performed respectively.The Pearson correlation analysis and the self-constituent ratio of mild,moderate and severe factors of the scale and AHI,ODI,LSPO2 were carried out to explore the correlation and factor distribution between depressed and unhappy state in patients with OSAHS.Results:1.General data analysis:there was no significant difference in sex and age among the three groups(P>0.05).2.Comparison of the scores of TCM depression and discomfort scale among the three groups:there were significant differences among the three groups in the total score of TCM depression state and the scores of each subscale.The total score of mild OSAHS patient scale was 1370,in which the factors of emotional depression,mental injury,qi stagnation,qi stagnation,trunk and limbs,and sleep disorder were 727,98,170,101,273,respectively,among which the factors of emotional depression,mental injury,qi stagnation,head and face,qi stagnation and limb stagnation,sleep disorder were 727、98、170、101、273 respectively.Accounted for 53.07%、7.15%、12.41%、7.37%and 19.93%,respectively.The total score of moderate OSAHS scale was 1865,including depression factor,mental injury factor,head stagnation factor,qi stagnation torso and limb factor,sleep disorder factor,accounting for 11.85%、5.74%、45.63%、31.69%and 5.09%,respectively,and accounted for 11.85%,5.74%,45.63%,31.69%and 5.09%,respectively,and accounted for 11.85%,5.74%,45.63%,31.69%and 5.09%,respectively.The total score of severe OSAHS scale was 2916,including depression factor,mental injury factor,head stagnation factor,qi stagnation trunk and limb factor,sleep disorder factor,accounting for 20.44%、27.64%、25.48%、18.90%and 7.54%,respectively.3.Correlation analysis:through the correlation analysis between the severity of depression and the related indexes of obstructive sleep apnea hypopnea syndrome,such as sleep apnea hypopnea index(AHI),minimum oxygen saturation(LSaO2)and oxygen reduction index(ODI),P=0.00,0.01,0.00 respectively,all<0.01.the results showed that the correlation coefficient between the total score of depression and discomfort scale and AHI、ODI and LSaO2 was 0.988,respectively.-0.352 and 0.931,suggesting that the state of depression and discomfort was highly linearly positively correlated with AHI,highly linearly positively correlated with ODI,and negatively linearly correlated with LSaO2.Conclusion:The score of depression scale was positively correlated with sleep apnea hypopnea index(AHI)and oxygen reduction index(ODI),and the lowest oxygen saturation(LSaO2)was negatively correlated with sleep apnea hypopnea index(ODI),which suggested that the degree of obstructive sleep apnea hypopnea syndrome increased with the aggravation of depression.In the scale,emotional depression factors and sleep disorder factors were mainly distributed in mild obstructive sleep apnea hypopnea syndrome,qi stagnation head and face factor and qi stagnation trunk and limb factors were mainly distributed in moderate obstructive sleep apnea hypopnea syndrome.The mental injury factor was mainly distributed in severe obstructive sleep apnea hypopnea syndrome.