Study Of Macular Vascular Density Change In Myopia Anisometropia Children Who Wear Monocular Ortho-k Based On OCTA

Objective:Before and after wearing orthokeratology,the diopter,eye axis,thickness of the central concave choroid,and retinal blood flow density of myopic eyes and relatively good eyes were observed before and after the wearing of orthokeratology in one eye with myopia anisometropia.Methods:Selection on April 1,2020 to March 1,2021 eye center of nanchang university the second affiliated hospital of myopic anisometropia monocular wearing orthokeratology children 21 cases,including wearing orthokeratology eye(high number of eye,21 eyes)into eye group,the other(0.50 D≤ SE≤ 0.50 D)into the healthy eye group(21 eyes);Another select normal eyesight into normal control group of 30 cases of children,diopter range of(0.50 D ≤ SE ≤ 0.50 D),follow-up observation on right eye.Using OCTA macular vascular scanned for client,foveal centered 3 * 3 mm to OCTA range scanning mode,after the completion of the scanning system automatic layering generated deep shallow retinal capillary plexus(SCP)and retinal capillary plexus(DCP);And in children with monocular 3 mo after wearing orthokeratology,6 mo,9 mo,12 mo follow-up its basic situation and shallow capillary density(SCPVD)and deep capillary density(DCPVD),the change of the thickness of the choroid.SPSS 26.0 was used for data analysis,and the measurement data were described by mean ± standard deviation.One-way ANOVA/repeated measures ANOVA were used for data conforming to normal distribution,and Kruskal-Wallis test was used for data conforming to normal distribution.Results:1.General situation: eye group of IOP after wearing orthokeratology,corneal endothelial CD had no significant change,there was no statistically significant difference(P > 0.05).After wearing orthokeratology for one year,the eye axis(AL)and equivalent spherical mirrors(SE)increased compared with before,statistically significant difference(P < 0.05),and the risk of eye growth rate is lower than the healthy eye and normal eye,difference is statistically significant.2.Macular vascular density(VD): baseline data display SCPVD and DCPVD with eye group lower than the healthy eye group and normal control group,difference has statistical significance(P < 0.05);Both the eye and the contrast between SCPVD and DCPVD normal eyes are not statistically significant(P > 0.05);Eye group after wearing orthokeratology SCPVD and DCPVD compared with wear mirror are lower,the difference was statistically significant(P < 0.05).And SCPVD and DCPVD of eye drop lower than the healthy eye and normal eye,statistically significant difference(P < 0.05);3.SFCT: The baseline data showed that the SFCT in the affected eye group was lower than that in the healthy eye group and the normal control group,and the difference was statistically significant(P<0.05);the SFCT comparison between the healthy eye group and the normal eye group was not statistically significant(P>0.05);the SFCT increased after the patient eye group wore orthokeratology(P<0.05);the SFCT decreased between the healthy eye group and the normal control group(P<0.05);Conclusion:1.Wearing orthokeratology in one eye in children with myopic refractive error reduces the decline in SCPVD and DCPVD,resulting in an increase in the thickness of the subcutaneous choroidal membrane of the macular center.2.Wearing orthokeratology in one eye in children with myopic refractive error can delay the growth rate of the eye axis and diopter,and the effect on intraocular pressure and corneal endothelial cell density is not obvious.