Effect Of High Frequency Chest Wall Oscillation Ventilation Combined With Ultrasonic Atomization In Patients With Acute Exacerbation Of Chronic Obstructive Pulmonary Disease

Objective:To evaluate the effect of high-frequency Chest Wall Oscillation Ventilation（HFCWO）combined with ultrasonic atomization on the treatment of patients with acute exacerbation of chronic obstructive pulmonary diseases（AECOPD）.Methods:A total of sixty AECOPD patients hospitalized within the Department of Respiratory Medicine,The First Hospital of Shanxi Medical University from Oct 2019 to June 2021were haphazardly divided into matched group and experimental group,with thirty patients in every group.The matched group was given standard drug therapy,whereas the experimental group was given HFCWO combined with ultrasonic atomization therapy on the basis of standard drug therapy.Changes in blood gas analysis（Pa O₂,Pa CO₂,Sa O₂）,6MWD,Borg score,cough expectoration score,m MRC score,CAT score and length of hospital stay in two teams were observed before treatment and one week after treatment.Results:The results of this study showed that intra-group comparisons were made between the experimental group and the matched group,and there have been statistically important variations altogether indicators after and before treatment（P<0.05）.After treatment,compared with the matched group,the blood gas analysis（Pa O₂,Pa CO₂,Sa O₂）indexes of patients within the experimental group were considerably improved compared with the matched group.Compared with the matched group,patients within the experimental group had longer 6MWD,lower cough and sputum score and Borg score,and shorter hospital stay,with statistically important variations（P<0.05）.The m MRC score and CAT score of the experimental group were below those of the matched group,however there was no applied math significance between the two groups（P>0.05）.Conclusion:HFCWO combined with ultrasonic atomization therapy can improve the cough sputum score,blood oxygen partial pressure and other blood gas indicators of AECOPD patients,promote sputum excretion,alleviate clinical symptoms and contract hospitalization time,which has important clinical practice value.