Correlation Between TIR And Urinary Microalbumin Levels In Type 2 Diabetic Patients

Objective: This study used the latest ambulatory glucose monitoring system to quantify blood glucose to derive TIR and further investigate the correlation between TIR and urinary microalbumin levels.Methods: 126 patients with type 2 diabetes mellitus who were hospitalized in our department from January 2020 to March 2022 were included in this study,and a 24-hour urinary microalbumin of 30 mg was used as the starting point.A binary logistic regression model was used to analyze the risk factors of urinary microalbumin level,and the correlation between the indexes in the two groups was analyzed and compared.Results: 1.The differences in age,disease duration,mean glucose,TIR,TBR,TAR,glycated haemoglobin,triglycerides,HDL,LDL,e GFR,creatinine,cystatin C,and coefficient of variation between the two groups were statistically significant(P < 0.05).2.TIR,LDL,cystatin C,and coefficient of variation were associated with the occurrence of urinary microalbumin(P < 0.05).3.3.There was a negative correlation between TIR and urinary microalbumin levels(P < 0.05);LDL,cystatin C,and coefficient of variation were positively correlated with 24 h urinary microalbumin levels(P < 0.05).Conclusion: TIR was negatively correlated with urinary microalbumin levels in type 2 diabetic patients,and urinary microalbumin increased significantly when TIR levels decreased.As an important indicator of blood glucose monitoring,TIR can well evaluate the glycemic control of diabetic patients and predict the occurrence of microalbuminuria.