Investigation Of Helicobacter Pylori Infection And Its Relationship With Risk Factors Of Arteriosclerosis In Physical Examination Population In Western Guangxi

Objective:To investigate the infection of Helicobacter pylori(H.pylori)in the physical examination population in western Guangxi,and to analyze the correlation between H.pylori infection and risk factors of arteriosclerosis.Methods:Methods: From January 2021 to December 2021,a retrospective analysis of9,780 permanent residents in western Guangxi who underwent physical examination in the Health Checkup Management Center of Southwest Hospital Affiliated to Youjiang Medical College for Nationalities was retrospectively analyzed.The basic information of all included patients was extracted from the hospital case system,including age,gender,occupation,height and weight,history of diabetes,history of hypertension,history of other diseases,drug history,and smoking history.At the same time,the following physical examination results of all included patients were collected: including carbon 14 urea breath test,blood pressure test,blood sugar test,liver function test(alanine aminotransferase,aspartate aminotransferase),blood lipid test(high-density lipoprotein cholesterol,triglyceride,low density lipoprotein cholesterol,homocysteine).The H.pylori infection status of healthy people in western Guangxi was analyzed and analyzed by gender(male,female),age(less than 35 years old、35～50、51～65、more than 65 years old,unit year),ethnicity(Han nationality),Zhuang,other ethnic groups),occupations(civil servants,workers,teachers,other occupations)were divided into groups to observe the infection rate of each group;at the same time,the differences in blood pressure,blood sugar and blood lipids between H.pylori-negative people and H.pylori-positive people were analyzed.Results:(1)The overall infection rate of H.pylori in healthy physical examination population in Western Guangxi is 33.64%,among which the infection rate of male population is 34.11%;The infection rate of female population was 32.42%;The infection rate of less than35 years old was 33.65%,that of 35 ～ 50 was 34.64%,that of 50 ～ 65 was 32.69%,and that of more than 65 years old was 29.77%;The infection rate of Han population was 32.46%,that of Zhuang population was 34.41%,and that of other ethnic groups was 32.25%;The infection rate of civil servants was 36.12%,that of workers was 35.88%,that of teachers was 28.05%,and that of other occupations was 29.54%.There was no relationship between H.pylori infection and gender,age,nationality and occupation in healthy people in Western Guangxi(P > 0.05).(2)In the health examination population in Western Guangxi,the diastolic blood pressure of H.pylori positive people is 75.37 ± 12.53 mm Hg,the systolic blood pressure is126.19 ± 18.05 mm Hg,the average arterial pressure is 92.31 ± 13.80 mmhg,and the diastolic blood pressure of H.pylori negative people is 71.91 ± 11.47 mm Hg,the systolic blood pressure is 116.09 ± 13.20 mmhg,and the average arterial pressure is 86.64 ± 11.35 mmhg H.pylori.The diastolic blood pressure,systolic blood pressure and mean arterial pressure of H.pylori negative people were significantly lower than those of H.pylori positive people(P < 0.05).(3)There were no differences in gender,age,body mass index,alanine aminotransferase,aspartate aminotransferase,high-density lipoprotein cholesterol,and homocysteine between H.pylori-positive and H.pylori-negative people in the healthy population in western Guangxi(P>0.05)The blood glucose,triglyceride and low density lipoprotein cholesterol in H.pylori positive population were significantly higher than those in H.pylori negative population(P<0.05).Conclusion:(1)The overall infection rate of H.pylori was 33.64% among the health check-up population in western Guangxi,and the infection was not related to gender,age and ethnicity,and the infection was related tooccupation.(2)In the health examination population in Western Guangxi,the average values of blood pressure,blood glucose,triglyceride and low density lipoprotein cholesterol related to arteriosclerosis risk factors in H.pylori positive population are significantly higher than those in H.pylori negative population,and H.pylori positive population may increased risk of atherosclerosis.