| Objective:Prehypertension is the incubation period that developed normal blood pressure to hypertension and the reserve power that increased the incidence of hypertension. It is meaningful to study the epidemiological status and risk factors of prehypertension to prevent and reduce the development of hypertension. The recent researches showed that prevalence characteristics and related factors of hypertension were different among ethnic groups, regions and populations. At present, the study of prehypertension in Guangzhou is common in community residents, and lack of epidemiological data on the hypertension in young and middle aged people.In this study, the influence factors and status of prehypertension in young and middle aged check-up population were analyzed. The influence factors of hypertension were explored to provide a theoretical basis for the further development of prevention and treatment of prehypertension.Method:This study was relied on the data bank of young and middle aged health check-up population of a class A tertiary general hospital in Guangdong province in 2015. Total10464 adults were investigated and 9540 were young and middle aged. Using Simple random sampling method, 733 young and middle aged health check-up population were selected.Their demographic data, health status, and dietary status were analyzed.General data of the normal quantitative data was shown with Mean±SD and the non-normal distribution of quantitative data was shown with Median±IQR. The t test was used to verify mean differences between the two groups of samples, and the ANOVA was used to comparedifferences among the groups. The chi-square test was used to analyze the differences of prevalence of prehypertension between two groups or more sets of samples. Principal Components Analysis(PCA) of Factor(FA) was used to identify dietary patterns. The single and multi-factor logistic regress methods were used to explore the influence factors of prehypertension. All statistical tests are bilateral test, set inspection level α=0.05, P<0.05 as the difference is significant.Results:1. The incidence of prehypertension among young and middle aged health check-up populationStudy was concluded in 10464 individuals. The incidence of prehypertension among10464 health check-up population was 36.7%, while it was significantly higher in males(39.9% vs 31.8%, P<0.001). Normal high blood pressure people were mainly distributed from 18 to 45. Prehypertension people were mainly distributed from 45 to 65.The incidence of prehypertension among 9540 young and middle aged health check-up population was 36.6%, while it was significantly higher in males(40.0% vs 30.7%, P<0.05)and middle aged(38.7% vs 34.6%, P<0.001).The incidence of prehypertension among 733 young and middle aged health check-up population selected by 9540 cases was 35.1%, while it was significantly higher in males(39.6% vs 27.6%, P<0.05) and middle aged(38.3% vs 31.8%, P<0.05).2. Situations of prehypertension and the accompanying blood sugar and lipid metabolism dysfunction among young and middle aged health check-up populationThe incidence of prehypertension with abnormal glucose metabolism among 9540 young and middle aged health check-up population was 4.3%, while it was significantly higher in males(5.0% vs 2.8%, P<0.001) and middle aged(6.3% vs 2.1%, P<0.001). There were significantly higher mean TC, TG and BMI, as well as lower HDL-C, observed in Group(P<0.05).The incidence of prehypertension with dyslipidemia among 9540 young and middle aged health check-up population was 45.1%, while it was significantly higher in males(50.8% vs 38.9%, P<0.001) and middle aged(51.7% vs 41.6%, P<0.001). The incidences of high TG in males and high TC in females were significantly most prominent(28.2% and17.3%, respectively).3. Survey of food and nutrient intakeCompared to the recommended value by Chinese residents balanced diet pagoda, theintake of eggs and oil among 257 young and middle aged prehypertension population were all in line with the recommended value, and grains, soy, meat and were slightly more than the recommended value. fish, milk, vegetables, Fruits, and salt were less than the recommended value. The intake of cholesterol were within the recommended range, and the intake of dietary energy, dietary protein, fat and carbohydrates were higher than the recommended values, and only dietary fiber intakes were lower. The average daily intake of magnesium and iron were closed to the recommended value, accounted for 93.47% and96.15%. Dietary phosphorus, potassium, sodium, zinc, copper and manganese exceeded the recommended values. And calcium and selenium were significantly lower than the reference intake. Vitamin E intake closed to the reference, accounted for 95.86% and Vitamins B1, Vitamin B2, Vitamin C, niacin were higher than reference intake. Vitamin A intake lower than the dietary reference intakes. Dietary patterns included ”meat model”,“spice model”, “main vegetables mode” and ”high protein mode”.4. Analysis of influence factors of prehypertension among young and middle aged health check-up populationLogistic regression analysis among 9540 in young and middle aged population revealed that age(OR=1.586, 95%CI=1.430-1.758), total cholesterol(OR=1.201, 95%CI=1.062-1.3580), triglyceride(OR=1.141,95%CI=1.058-1.230), uric acid(OR=1.259, 95%CI=1.115-1.421), overweight/obesity(OR=1.844, 95%CI=1.701-2.000), heart rate(OR=1.393, 95%CI=1.302-1.491) increased the risk of prehypertension. But female(OR=0.590,95%CI=0.530-0.656) were negative influencing factors for prehypertension.Logistic regression analysis among 733 in young and middle aged population revealed that age(OR=2.201, 95%CI=1.379-3.511), drinking(OR=1.982, 95%CI=1.342-2.927) increased the risk of prehypertension. But dietary milk intake(OR=0.590, 95%CI=0.530-0.656)and dietary magnesium intake(OR=0.978, 95%CI=0.964-0.992) were negative influencing factors for prehypertension.Conclusion:1. The incidence of prehypertension among 9540 young and middle aged health check-up population was 36.6%, remained at a high level, while it was significantly higher in males and middle aged.2. Prehypertension is closely correlated with glucose and lipid metabolism dysfunction,and the investigation on the prevalence of prehypertension complicated with blood sugar and lipid metabolism dysfunction among 3491 young and middle aged health check-uppopulation is unpromising. People with abnormal glucose metabolism have more cardiovascular risk factors. The screening of prehypertension should be advocated, and those with blood sugar and lipid metabolism dysfunction should be considered as high-risk population of cardiovascular and cerebrovascular diseases.3. 257 young and middle aged residents had been consumed more meat, higher energy and fat. The dietary phosphorus, potassium, sodium, zinc, copper and manganese exceeded the recommended values. The intake of calcium, selenium, Vitamin A is lower than the recommended value at different levels.4. Logistic regression analysis revealed that dietary milk intake and dietary magnesium intake were negative influencing factors for prehypertension, but age, drinking, total cholesterol, triglyceride, uric acid, overweight/obesity and heart rate increased the risk of prehypertension. |
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