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Study On Homology Of Malignant Tumors Of Digestive System By MR High Definition Diffusion Weighted Imaging Combined With Energy Spectrum CT

Posted on:2023-07-09Degree:MasterType:Thesis
Country:ChinaCandidate:Z X WangFull Text:PDF
GTID:2544306848994269Subject:Imaging and nuclear medicine
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Objective:To investigate the diagnostic value of MR high-definition diffusion weighted imaging combined with energy spectrum CT imaging in the homology of digestive system malignant tumors.Methods:50 patients with malignant tumors of digestive system and solid organ metastasis were selected,including 63 primary foci and 157 metastases,including 19 cases of gastric cancer(53 liver metastases,1 adrenal metastasis and 1ovarian metastasis),15 cases of rectal cancer(40 liver metastases),11 cases of colon cancer(32 liver metastases and 1 adrenal metastasis)There were 5 cases of pancreatic cancer(29 liver metastases).All patients were scanned simultaneously by high-definition diffusion-weighted imaging(resolve-dwi)and three-phase enhanced energy spectrum CT.The relevant parameters of resolve-dwi and energy spectrum CT scanning of primary and metastatic lesions,such as iodine concentration,effective atomic number and ADC value,were obtained;The CT values of the region of interest were measured at 40 ke V and 100 ke V single energy,and the slope of the energy spectrum attenuation curve was calculated.The number and rate of lesions detected by resolve-dwi,energy spectrum CT and their combination were compared.The energy spectrum data,ADC value and the number of lesions were statistically analyzed by independent sample t-test;The detection rate was statistically analyzed by chi-square test.Results:1.The energy spectrum curves of primary and metastatic lesions of digestive system malignant tumors in arterial phase,a falling pattern in the intravenous and delayed phases,and the difference of energy spectrum curve at40 ke V was the most obvious.With the increase of energy,the shape of energy spectrum curve tended to be consistent;The effective atomic number histogram showed that the overlap of primary and metastatic lesions was partially consistent.2.There were significant differences in iodine concentration and ADC value between primary and metastatic tumors of digestive system in three stages(all P<0.05);There was no considerable variation in the slope of energy spectrum attenuation curve and effective atomic number between primary and metastatic tumors of digestive system in three stages(P>0.05).3.The number of primary lesions(1.22±0.34)and metastatic lesions(3.10±1.99)detected by resolve-dwi combined with energy spectrum CT were more than that detected by resolve-dwi(1.12±0.75),(2.84±2.09)and energy spectrum CT(0.90±0.86),(2.48±1.95);The detection rates of primary lesions and metastatic lesions were 96.83% and 98.73%,which were higher than 88.89% and 90.45% of resolve-dwi and 71.43% and 78.98% of energy spectrum CT(P < 0.01).Conclusions:Energy spectrum attenuation curve slope and effective atomic number histogram of three-phase enhanced scanning of energy spectrum CT.It suggests that the primary focus is homologous with the metastatic focus.Both energy spectrum CT and resolve-dwi have better diagnostic efficiency,and the diagnostic efficiency of resolve-dwi combined with energy spectrum CT is better than that of both alone.In conclusion,resolve-dwi combined with energy spectrum CT can be used as an effective method to evaluate the homology of digestive system malignant tumors and provide a reliable basis for tumor traceability.
Keywords/Search Tags:RESOLVE-DWI, GSI, Malignant tumor of digestive system, Metastasis, Homology
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