| Objective: To explore the medication rules of Zibo Traditional Chinese Medicine Hospital for the treatment of pediatric pneumonia and wheezing,and to provide a reference for the use of traditional Chinese medicine for the treatment of pediatric pneumonia and wheezing.Methods: Children with pneumonia and cough who were hospitalized in the pediatrics Department of Zibo Hospital of Traditional Chinese Medicine from July 2020 to June 2022 were selected as the research objects.According to the diagnostic criteria of pneumonia and cough,combined with the inclusion criteria and exclusion criteria,421 cases of pneumonia and cough were selected.Extract the patient’s information such as gender,age,syndrome,length of stay and application of traditional Chinese medicine prescription and input it into the TCM inheritance assistance platform system(V2.5).Select the "prescription analysis" module and click the two plates of "Statistical report" and "data analysis".Statistical analysis was carried out on the input data,such as disease syndrome statistics,drug frequency statistics,four qi and five flavor statistics and normalization statistics,analysis of compatibility prescriptions and network visualization diagram.Results: 1.A total of 421 cases were included in this study,including228 male children and 193 female children,most of whom were 0-3 years old;2.This study involved 201 traditional Chinese medicines with a cumulative frequency of 4448 times.The top 10 Chinese medicines were bitter almond(290times),ephedra(268 times),plaster(216 times),glycyrrhiza(158 times),scutellaria scutellaria(153 times),pinellia platycosa(150 times),platycosa platycosa(138 times),perilla seed(110 times),mulberry white bark(107 times),draba nemorosa(105 times),etc.The main use of phlegm-reducing cough and antiasthmatic drugs,heat-clearing drugs,tonifying drugs,anti-surface drugs,blood-activating drugs and blood-stasis drugs,qi drugs,water and moistening drugs;3.The study showed that phlegm-heat closing the lung was the main syndrome,followed by wind-heat closing the lung and deficiency of lung qi.The four qi were mainly cold,warm and flat,the five tastes were mainly bitter,plicative and sweet,and the lung,stomach and spleen were mainly in the conversion to meridian;4.27 pairs of commonly used drug combinations were obtained,including 10 traditional Chinese medicines such as gypsum,ephedra,bitter almond,scutellaria scutellaria and Houttuynia Cordata;5.26 results were obtained after analysis of association rules;6.The study found that there were 44 groups of drug pairs with correlation coefficient above 0.015,among which the correlation degree between atractylodes and yam was the highest;7.The study summarized 7 core drug prescriptions and discovered 6 new prescriptions.Conclusion: 1.Phlegm-heat closing lung is the dominant syndrome type of pneumonia and cough;2.Clinical drug use is flexible,combined with cold and heat,attack and tonic treatment,mainly to clear heat and promote lung,cough and phlegm,specimen consideration;3.Six new prescriptions were obtained,and the addition and subtraction of clinical syndrome differentiation were applied,which provided theoretical basis for exploring effective treatment of pneumonia and cough. |