Effect Of Adding Or Reducing Taohong Siwu Decoction On Residual Pain After PVP For Osteoporotic Vertebral Compression Fracture

Objective : By observing the clinical effect of addition and reduction of Taohong Siwu decoction on residual pain after PVP operation for osteoporotic vertebral compression fracture with blood stasis and qi stagnation,and discussing its effectiveness and safety,it provides a new method and a new basis for clinical treatment of residual pain after PVP operation with traditional Chinese medicine for the treatment of residual pain after PVP operation for osteoporotic vertebral compression fracture with blood stasis and qi stagnation.Methods:Sixty patients with osteoporotic vertebral compression fracture who were admitted to the Spinal Surgery Department of Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine from January 2022 to December 2022 and who met the diagnosis and inclusion criteria of this study were selected.They were randomly divided into treatment group and control group,with 30 cases in each group.The treatment group began to take Jiao-minus Peach red Siwu decoction on the first day after PVP;The control group started to take imericoxib tablets on the first day after PVP.All patients in both groups were given medication for 2 weeks and stopped after 2 weeks.Follow-up observation was continued for 2 weeks after drug withdrawal.Preoperative basic information,alanine aminotransferase(ALT)and aspartate aminotransferase(AST)were recorded and collected.visual analogue scale(VAS)and Oswestry Disability Index(ODI)on the day after surgery;VAS score and ODI score 1 week after medication;VAS score,ODI score,ALT,AST 2 weeks after medication;VAS score,ODI score,ALT,AST 4 weeks after medication.All the data collected were sorted out and analyzed by SPSS22.0 statistical software.a=0.05 was the test level,P<0.05 was considered statistically significant.Results : 1.The gender and age of the two groups showed no statistical significance(P > 0.05),indicating comparability.2.VAS score: The VAS score of the two groups after PVP was statistically analyzed,showing no statistical significance(P > 0.05),which was comparable.VAS scores of 1 week,2 weeks and 4 weeks after medication in the treatment group were compared with VAS scores on the day after surgery within the group.Statistical test showed that the differences were statistically significant 1 week,2 weeks and 4 weeks after medication(P< 0.05).VAS scores of the control group 1 week,2 weeks and 4 weeks after medication were compared with VAS scores on the day after surgery within the group.Statistical test showed that the differences were statistically significant 1 week,2 weeks and 4 weeks after medication(P < 0.05).The VAS scores of the two groups on the day after surgery,1 week after medication,2 weeks after medication and 4 weeks after medication were compared between the two groups.The statistical test showed that there was no significant difference in VAS score on the day after surgery(P > 0.05),which was comparable.There was no significant difference in VAS scores between 1 week and 2 weeks after medication(P > 0.05).The VAS score at 4weeks after medication was significantly different(P < 0.05).3.ODI score: Statistical analysis of ODI score after PVP between the two groups showed no statistical significance(P > 0.05),indicating comparability.The ODI scores of the treatment group at 1 week,2 weeks and4 weeks after medication were compared with the ODI scores on the day after surgery within the group.Statistical test showed that the ODI scores of the treatment group at 1 week,2 weeks and 4 weeks after medication had statistical significance(P < 0.05).The ODI scores of the control group at 1week,2 weeks and 4 weeks after medication were compared with the ODI scores on the day after surgery within the group.The statistical test showed that the ODI scores at 1 week,2 weeks and 4 weeks after medication had statistical significance(P < 0.05).The ODI scores of the two groups on the day after surgery,1 week after medication,2 weeks after medication and 4weeks after medication were compared and analyzed between groups.The statistical test showed that there was no significant difference in ODI score on the day after surgery(P > 0.05),which was comparable.The ODI score of 1week after medication,2 weeks after medication and 4 weeks after medication had statistical significance(P < 0.05).4.Overall efficacy: 4 weeks after taking the drug,8 cases in the treatment group were cured,21 cases were improved,and 1 case was not cured.The total effective rate was 96.7%.In the control group,2 cases were cured,26 cases were improved and 2 cases were not cured.The total effective rate was 93.3%.The statistical test showed that the overall curative effect of the two groups was statistically different(P < 0.05).Conclusion:Modified Taohong Siwu Decoction in the treatment of residual pain after PVP surgery for osteoporotic vertebral compression fracture with blood stasis and qi stagnation is effective,and can improve the movement function of the patient’s waist and back,with safety.