Related Research On Hidden Blood Loss And Its Risk Mechanism In Elderly Total Knee Arthroplasty

Objectives To explore the related factors of increased hidden blood loss(HBL)after total knee arthroplasty(TKA)in elderly patients with knee osteoarthritis,to further clarify the risk factors leading to high HBL volume,and to achieve perioperative management of elderly patients undergoing TKA treatment.Scientific evaluation of the patient is carried out,a reasonable diagnosis and treatment plan for TKA is formulated,and the perioperative blood management system for elderly patients undergoing TKA treatment is improved,so as to enable the patients to obtain the best clinical treatment effect.Methods A retrospective analysis of 188 patients who received TKA in Tangshan Second Hospital(Orthopaedic Hospital of North China University of Science and Technology)from January 2018 to October 2020 and met the inclusion and exclusion criteria of this study was performed using univariate analysis.)and multiple linear regression analysis to study the influencing factors of hidden blood loss after TKA in elderly patients.The patient’s gender,age,surgical side,Kellgren-Lawrence classification,body mass index,hypertension,coronary heart disease,diabetes,smoking,operation time,postoperative limb position,and prosthesis type were collected.,whether blood transfusion,preoperative hemoglobin(Hemoglobin,HGB),preoperative platelet count(Platelet,PLT),preoperative hematocrit(Hematocrit,HCT),postoperative hematocrit,preoperative blood volume,apparent blood loss,A total of 20 factors related to postoperative C-reactive protein that may be associated with hidden blood loss after TKA were included in this study.Results A total of 188 elderly patients undergoing TKA were included in this study.Gender,age,surgery side,Kellgren-Lawrence classification,body mass index,hypertension,coronary heart disease,diabetes,smoking,operation time,postoperative limb position,prosthesis type,Blood transfusion or not,preoperative hemoglobin content(HGB),preoperative platelet count(PLT),preoperative hematocrit(HCT),postoperative hematocrit,preoperative blood volume,apparent blood loss,postoperative C-reactive protein level A total of 20 observation indicators were subjected to independent sample t-test.The analysis results showed that different gender,age,preoperative hemoglobin content,preoperative blood volume,preoperative hematocrit,postoperative hematocrit,apparent blood loss,postoperative C The hidden blood loss after TKA,such as reactive protein level,was compared,and the difference was statistically significant(P value < 0.05).Different surgical side,Kellgren-Lawrence classification,body mass index,operation time,postoperative limb position,prosthesis type,preoperative platelet count(PLT),whether the patient has hypertension,coronary heart disease,diabetes,whether blood transfusion,There was no significant difference in the hidden blood loss after TKA,such as smoking or not(P value>0.05).Statistically significant observation indicators(gender,age,preoperative hemoglobin content,preoperative blood volume,preoperative hematocrit,postoperative hematocrit,apparent blood loss,postoperative C-reactive protein)were screened out by univariate analysis.A total of 8 items were further subjected to multiple linear regression analysis,and the results showed that gender,preoperative hematocrit,postoperative hematocrit,apparent blood loss,and preoperative blood volume were the most important factors affecting the hidden blood loss after TKA in elderly patients.independent risk factors.Conclusions Gender,postoperative C-reactive protein content,preoperative hematocrit,postoperative hematocrit,overt blood loss,and preoperative blood volume were independent risk factors for latent blood loss after TKA in elderly patients.Elderly male patients with knee osteoarthritis treated with total knee arthroplasty have a relatively higher risk of postoperative hidden blood loss.It is necessary to pay close attention to the changes of blood routine indicators during the perioperative period,prepare for blood management in advance,and reduce the risk of blood loss as much as possible.The postoperative inflammatory response of patients can avoid excessive postoperative hidden blood loss and affect the recovery of knee joint function of patients.Figure2;Table4;Reference 145...