| Objective:To investigate and analyze the characteristics of painless gastroenteroscopy and the risk factors of gastrointestinal cancer in patients with CAG and colorectal polyps.Methods:The name,gender,age,height,weight and other general data of the patients undergoing painless and routine gastroenteroscopy were collected.A face-to-face questionnaire survey was conducted on all the patients undergoing gastroenteroscopy before the examination.The questionnaire contents included the patients’ tolerance to the examination,the sources of the examination expenses,the occupation and educational level of the patients,etc.At the same time,dietary habits and past medical history were investigated among those who volunteered to fill in the questionnaire.Survey results were collected in sequence according to the sequence of questionnaire coding.After the completion of the questionnaire,gastroscopy and colonoscopy reports and corresponding pathological data of those who volunteered to fill in the questionnaire were collected.Based on the high-risk groups of gastric cancer defined by the 2020 Guidelines for early gastric cancer Screening and the Asia-Pacific colorectal cancer prediction and evaluation model in the Consensus on early diagnosis and early treatment of colorectal cancer,the gastroenteroscopy subjects who filled in the questionnaire were stratified and then grouped.The gastric cancer risk group was divided into high-risk and non-high-risk groups,and the colorectal cancer risk components were low-risk group,medium-risk group and high-risk group.According to the results of the Asia-Pacific colorectal cancer assessment model,those who scored 0-1 were in the low-risk group.A score of 3-4 was considered as a medium-risk group,while a score of 4-7 was considered as a high-risk group.Stratified analysis was made on the dietary habits and related medical history of the subjects in the above groups,and the possible risk factors of gastrointestinal cancer in patients with CAG and colorectal polyps were explored in the dietary habits and related medical history.Results:1.General data: A total of 200 cases of questionnaires were collected in this survey,including 140 cases of CAG and 108 cases of colorectal polyps detected by painless and routine gastroenteroscopy combined examination,and 171 cases of complete questionnaire data were included in the population characteristics survey of painless and routine gastroenteroscopy,including 90 cases of males and 81 cases of females.The average age of respondents was(47.42±14.11)years old;Stepwise stratified analysis showed that there were 72 cases in the painless gastroenteroscopy group and 99 cases in the conventional group.The statistical results showed that the endoscopic CAG detection rate of painless group was 63.6%,and that of conventional group was 66.7%.There was no statistical significance in the detection rate of CAG between the two groups(P>0.05).The detection rate of colorectal polyps was 73.7% in the painless gastroenteroscopy group and 26.3% in the conventional gastroenteroscopy group.The difference in the detection rate of colorectal polyps between the painless gastroenteroscopy group and the conventional group was statistically significant(P=0.003).2.Univariate analysis was carried out on occupation,educational level,examination cost and other characteristics between the painless gastroenteroscopy group and the conventional gastroenteroscopy group.The results showed that there were significant differences between the painless gastroenteroscopy group and the conventional group in the cost source,occupation and educational level of the examiner,and the differences were statistically significant(P< 0.05).3.There was statistical significance between the painless group and the conventional group in the degree of tolerance to gastroenteroscopy(P< 0.05).After risk factors assessment,the high-risk groups of gastric cancer were divided into a high-risk group of 85 cases and a non-high-risk group of 55 cases.The diet habits and related disease history of the subjects in the two groups were examined.Univariate analysis results showed that different gender,age,smoking history,drinking history and BMI value were related factors for the possible occurrence of gastric cancer in CAG patients.The difference was statistically significant(P< 0.05),and the results of multivariate analysis of the dietary habits and related disease history of the two groups showed that age was an independent risk factor for gastric cancer in CAG patients(P< 0.05,OR > 1).After assessing the risk of colorectal cancer,the subjects were divided into low-risk,medium-risk and high-risk groups for analysis.43 cases were in the low-risk group,51 cases in the medium-risk group,and 14 cases in the high-risk group.Univariate analysis was carried out on the diet habits and related disease history of the subjects in the three groups,and the results showed that drinking and fried food were related factors for the risk of colorectal cancer in patients with colorectal polyps.The differences were statistically significant(P=0.010,P=0.001).Multivariate logistic regression analysis showed that a history of fatty liver was an independent risk factor for colorectal cancer in patients with colorectal polyps(P< 0.05,OR > 1).Conclusions:1.Compared with conventional gastroenteroscopy,painless gastroenteroscopy has a higher detection rate for colorectal polyps,so the clinical application of painless gastroenteroscopy should be increased.2.Occupation of patients undergoing painless gastroenteroscopy,sources of examination expenses and cognition of gastroenteroscopy are related factors that mainly affect the application of painless gastroenteroscopy,and the utilization rate of painless gastroenteroscopy should be improved through publicity and education.3.Age is an independent risk factor for gastric cancer in patients with CAG;History of fatty liver disease and diet dominated by pork or processed meat are independent risk factors for colorectal cancer in patients with colorectal polyps.Early active intervention,treatment and dietary changes can reduce the risk of gastrointestinal cancer in patients with CAG and colorectal polyps. |
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