Efficacy Analysis Of Thulium Laser En-bloc Resection Of Bladder Tumor Versus Plasm Akinetic Transurethral Resection Of Bladder Tumor For Non-muscle Invasive Bladder Cancer

Objective:To investigate the clinical efficacy of ThuLEBT in the treatment of non-muscle invasive bladder cancer(NMIBC)by comparing thulium laser en-bloc resection of bladder tumor(ThuLEBT)with plasmakinetic transurethral resection of bladder tumor(PK-TURBT)in terms of surgical risks and benefits.Methods:In this study,192 patients with non-muscle invasive bladder cancer(NMIBC)treated with thulium laser en-bloc resection of bladder tumor(ThuLEBT)or plasmakinetic transurethral resection of bladder tumor(PK-TURBT)were admitted to our hospital from September 2019 to January 2022.Among them,94 cases underwent thulium laser en-bloc resection of bladder tumor(ThuLEBT group)and 98 cases underwent plasmakinetic transurethral resection of bladder tumor(PK-TUTRBT group).Retrospectively,we analyzed the operating time,intraoperative bleeding,incidence of intraoperative closed nerve reflex and bladder perforation,postoperative bleeding time,postoperative indwelling urinary catheter time,postoperative hospital stay,incidence of postoperative bladder irritation sign,postoperative pathological myelomeningocele finding rate and postoperative bladder tumor recurrence rate in both groups.In this clinical study,all the measures involved that conformed to a normal distribution were represented as mean ± standard deviation,and the comparison of data between the 2 groups was performed by using the two independent samples t test.Statistical analysis of the count data between the 2 groups was performed using the χ2 test,and at P<0.05,there were differences between the two groups that were statistically significant.Results:(1)The postoperative bleeding time(1.62±0.67d),the mean postoperative catheterization time(2.77±0.81d),and the mean postoperative hospitalization time(3.97±0.99 d)in the ThuLEBT group were less than those in the PK-TURBT group(in order of comparison:2.10±0.68 d,3.46±0.93 d,and 4.60±1.02d).There was a statistical difference between the two(P<0.05).(2)The incidence of intraoperative closed-hole nerve reflex(0.0%)and postoperative bladder irritation sign(3.2%)in the ThuLEBT group was smaller than that in the PK-TURBT group(6.1%and 14.3%,in that order),with a statistical difference between the two groups(P<0.05).(3)The postoperative pathological tissue myelomeningocele detection rate(95.7%)and postoperative bladder tumor recurrence rate(5.3%)in the ThuLEBT group were smaller than those in the PK-TURBT group(84.7%and 16.3%,in that order)compared to the PK-TURBT group,which were statistically different(P<0.05).Conclusion:ThuLEBT has the advantages of shortening postoperative bleeding time,shortening postoperative ureter retention time,shortening postoperative hospitalizati-on time reducing the incidence of bladder irritation sign,avoiding the occurrence of closed nerve reflex,and reducing postoperative tumor recurrence rate,etc.ThuLEBT is safe and feasible in the treatment of non-muscle invasive bladder cancer and can be promoted in clinical practice.