Clinical Data Analysis Of Postmenopausal Women With Uterine Effusion

Object:To explore the related influencing factors of postmenopausal women with uterine effusion complicated with organic lesions and endometrial malignant lesions,so as to facilitate clinicians to divert diagnosis and treatment of patients,avoid increasing the economic burden of patients and prevent the waste of medical resources.Methods:Retrospective analysis of postmenopausal women who were admitted to the Second Hospital of Jilin University from November 2014 to November 2022 and who were diagnosed with uterine cavity separation or uterine cavity liquid dark area by gynecological ultrasound A total of 202 cases were screened out by inclusion and exclusion criteria.According to the final pathological results,they were divided into a simple effusion group and an organic lesion group.The organic lesion group was subdivided into a benign lesion group and a malignant lesion group by pathological results again.Information on age,menopausal timing,obesity,history of hypertension,history of diabetes,parity,nature and depth of uterine cavity fluid,single-layer endometrial thickness,related symptoms,whether combined with uterine cavity occupation,tumor markers(CA12-5,CA19-9),history of adnexal surgery,and history of malignant tumors of other organs were collected.Then a chi-square test and multivariate logistic regression statistical analysis were performed on these factors to finally determine the related influencing factors of postmenopausal women with uterine cavity effusion complicated by organic lesions and endometrial malignant lesions.Results:1.In this study,there were statistically significant in the history of hypertension,obesity,related symptoms,combined uterine space occupation,the nature of uterine effusion,the depth of uterine effusion,the thickness of single endometrium,and tumor markers between the simple effusion group and the organic lesion group(P <0.05).It shows that the above factors are related to postmenopausal women with uterine effusion complicated by organic lesions.After multivariate logistic regression analysis,it was found that related symptoms(vaginal bleeding,vaginal fluid,lower abdominal pain),combined uterine space occupation,the nature of uterine fluid(hematocele,empyema),the depth of uterine fluid>3cm,and single endometrial thickness≥0.3cm were independent risk factors.2.In the comparison between the benign lesion group and the malignant lesion group,there were statistically significant differences in the history of hypertension,history of diabetes,related symptoms,combined uterine space occupying,monolayer endometrial thickness,and tumor markers(P <0.05).It shows that the above factors are related to endometrial cancer in postmenopausal women with uterine effusion and organic lesions.Multivariate logistic regression analysis showed that combined uterine space occupying and abnormal tumor markers were independent risk factors.Conclusions:1.The majority of postmenopausal women with uterine cavity effusion have simple effusion with non-organic lesions,but for patients with a history of hypertension,obesity,related clinical symptoms(vaginal bleeding,fluid flow,lower abdominal pain),uterine space occupation,abnormal nature of uterine cavity effusion(hematocele,empyema),depth of uterine cavity effusion > 3cm,single-layer endometrial thickness0.3 cm,or abnormal elevation of tumor markers(CA12-5,CA19-9),one or more risk factors,one or more risk factors should be further examined to exclude endometrial lesions.2.For postmenopausal women with uterine effusion caused by organic lesions,patients with a history of hypertension,diabetes,related symptoms(vaginal bleeding),uterine space-occupying single-layer endometrial thickness > 0.5cm,and abnormally elevated tumor markers(CA12-5,CA19-9)should be more alert to the possibility of malignant endometrial lesions.3.For postmenopausal patients with uterine effusion without the above risk factors,this study believes that the risk of organic lesions is low,and the diagnosis and treatment can be appropriately relaxed.There is no need for expensive invasive operations,examinations,and treatments,but regular review is still needed.