| Objective:Through clinical investigation,this study analyzed the distribution chara-cteristics of traditional Chinese medicine constitution,syndrome type,anxie-ty state and related factors of patients with abnormal uterine bleeding of anovulatory type in perimenopausal period,and explored the internal relation-ship between traditional Chinese medicine constitution,syndrome type,anxiety state and related factors,combined with the diagnosis and treatment model of "disease differentiation-syndrome differentiation-body discrimina-tion" of traditional Chinese medicine and emotional therapy.In order to provide theoretical reference for the treatment of perimenopausal anovulation type abnormal uterine bleeding.Methods:In this study,193 patients diagnosed with perimenopausal anovulation abnormal uterine bleeding admitted to the gynecological clinic of the First Affiliated Hospital of Heilongjiang University of Chinese Medicine from December 2021 to February 2023 were investigated by questionnaires.General information,TCM constitution questionnaire,TCM syndrome questionnaire,self-rating anxiety scale and Pittsburgh Sleep Scale were collected.4 cases of invalid questionnaires were eliminated,and 189 cases meeting the criteria were finally included.The complete and effective data were sorted out and input into the computer,a database was established,and SPSS25.0 statistical software was used for analysis,and corresponding statistical results were obtained.Results:1.The TCM constitution distribution of perimenopausal patients with abnormal uterine bleeding of anovulatory type is as follows: Qi deficiency 69 cases(36.5%)> Yang deficiency 37 cases(19.6%)> Yin deficiency 28 cases(14.8%)> Qi stagnation 27 cases(14.3%)> peace 11 cases(5.8%)>dampness-heat 7 cases(3.7%)> blood stasis 5 cases(2.6%)> phlegmdampness 4 cases(2.1%)> characteristic quality 1 case(0.5%).2.The distribution of TCM syndrome types of patients with abnormal uterine bleeding without ovulation in perimenopausal period was in the following order: spleen deficiency syndrome 62 cases(32.8%)> blood stasis syndrome 37 cases(19.6%)> kidney qi deficiency syndrome 25 cases(13.2%)> kidney Yang deficiency syndrome 21 cases(11.1%)> blood deficiency heat syndrome 18 cases(9.5%)> kidney Yin deficiency syndrome 13 cases(6.9%)= blood deficiency heat syndrome 13(6.9%).3.In perimenopausal patients with abnormal uterine bleeding of anovulation type,there were statistically significant differences in the distribution of TCM syndrome type and physical type,number of abortion,course of disease,diet bias and pressure status(P < 0.05),but there was no statistical significance between TCM syndrome type and other general data(P > 0.05).Further Logistic regression analysis showed that spleen deficiency syndrome was positively correlated with qi deficiency quality,Yang deficien-cy quality and dietary bias.Kidney qi deficiency syndrome is positive-ly correlated with qi deficiency quality and course of disease.Kidney Yang deficiency syndrome was positively correlated with Yang deficiency quality and course of disease.Kidney Yin deficiency syndrome was positively correla-ted with Yin deficiency quality and abortion frequency.Blood stasis syndrome is positively correlated with qi stagnation,blood stasis and pressure.Blood-solid heat syndrome was positively correlated with Qi-stagna-tion and damp-heat.Blood deficiency heat syndrome is positively correlated with Yin deficiency.4.Among the patients in this survey,78 had anxiety and 111 had no anxiety.5.There were significant differences(P < 0.05)between the two groups of patients with and without anxiety in physical type,age,number of abortions,history of menstrual irregularities,course of disease,sleep status,anemia status,stress status and living environment distribution.Further Logistic regression analysis showed that,Qi-deficiency quality,Qi-stagnation quality,course of disease,sleep status and pressure status were all risk factors for patients with anxiety(P < 0.05).Conclusion:1.The traditional Chinese medicine constitution of perimenopausal patients with abnormal uterine bleeding of anovulatory type is mainly biased,with less peace and quality.Biased constitution mainly qi deficiency,Yang deficiency,Yin deficiency,qi depression.2.The main TCM syndromes of perimenopausal patients with abnormal uterine bleeding of anovulatory type are spleen deficiency syndrome and kidney deficiency syndrome(including kidney qi deficiency syndrome,kidney Yin deficiency syndrome and kidney Yang deficiency syndrome).3.The distribution of TCM syndromes of perimenopausal patients with abnormal uterine bleeding of anovulatory type can be affected by constitution type,number of abortion,course of disease,diet preference and stress.Qi deficiency quality,Yang deficiency quality and diet preference were related factors of spleen deficiency syndrome.Qi-deficiency quality and course of disease are related factors of kidney qi deficiency syndrome.Yang deficiency quality and course of disease are related factors of kidney Yang deficiency syndrome.Yin deficiency quality and abortion frequency were related factors of kidney Yin deficiency syndrome.Qi-stagnation quality,blood-stasis quality and pressure were related factors of blood-stasis syndrome.Qi-stagnat-ion quality and damp-heat quality were related factors of blood-solid heat syndrome.Yin deficiency is the related factor of blood deficiency heat syndro-me.4.Among the patients in this survey,the detection rate of anxiety was high,and mild anxiety was the main one.Physical type,age,number of abortion,history of irregular menstruation,course of disease,sleeping conditi-on,anemia,stress and living environment were associated with anxiety in perimenopausal patients with abnormal uterine bleeding of anovulatory type.Qi deficiency quality,qi stagnation quality,disease course,sleep condition and pressure condition are the risk factors of anxiety in perimenopausal patients with abnormal uterine bleeding of anovulatory type. |
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