| Objective:To observe the curative effect of salt-blocking moxibustion Wuzang Shu combined with routine acupuncture in the treatment of perimenopausal insomnia,so as to provide more effective treatment ideas and methods for the clinical treatment of perimenopausal insomnia patients.Methods:Sixty middle-aged female patients were enrolled in the clinical trial,and the 60 subjects were randomly divided into control group and treatment group by SPSS,with 30 subjects in each group.Control group Perimenopausal insomnia was treated by conventional acupuncture,the treatment group was treated by conventional acupuncture and combined with the salt-separating moxibustion Wuzangshu.The treatment time was 6 times per week,a total of2 weeks of treatment.Pittsburgh Sleep Quality Index(PSQI)score and Somatic Self-rating Scale(SSS)score,luteinizing hormone(LH),estradiol(E2),follicle stimulating hormone(FSH)and TCM symptom score as well as the different in curative effect of patients in both groups was observed before and after treatment.And then SPSS software was used for statistical analysis of the data.Results:1.PSQI score: the PSQI score,SSS score and TCM syndrome score of the two groups Score before enrollment was comparable,with no statistical significance(P>0.05).After 2 weeks of treatment,PSQI score,SSS score and TCM syndrome score all decreased significantly and the difference was statistically significant(P<0.05).But compared with the control group,PSQI score,SSS score and TCM syndrome score of the treatment group improved more observably,and the difference was statistically significant(P< 0.05).2.Laboratory test results: Patients in the treatment group and the control group were examined for serum hormone six items before treatment,record the results of FSH,LH,and E2,SPSS analysis showed no statistical significance(P > 0.05),the experimental data are comparable.After 2 weeks treatment,the indexes of FSH,LH and E2 in the treatment group and the control group were lower than before treatment,and the differences were statistically significant(P<0.05).However,the indexes of FSH,LH and E2 in the treatment group decreased more significantly than those in the control group and the difference was statistically significant(P<0.05).3.Evaluation of clinical curative effect: the total effective rate was96.56% in the treatment group and 82.14% in the control group.There was a significant difference in clinical efficacy between the two groups(P<0.05).The results showed that the total effective rate of the treatment group was striking better than that of the control group.Conclusion:1.The PSQI score,SSS score and TCM symptom score of perimenopausal insomnia were significantly improved by conventional acupuncture and salt-isolated moxibustion Wuzang Shu combined with conventional acupuncture.But,salt-separated moxibustion with Wuzang Shu combined with routine acupuncture has a more significantly improvement effect;laboratory indexes of FSH,LH and E2 showed that the laboratory indexes of both the treatment group and the control group were improved,but salt-repellant moxibustion with Wuzang Shu combined with routine acupuncture was more effective in improving the level of sex hormones in perimenopausal patients than conventional acupuncture.2.The curative effect of salt-separated moxibustion Wuzang Shu combined with conventional acupuncture in the treatment of perimenopausal insomnia is significantly higher than that of conventional acupuncture,and has no obvious adverse reactions and toxic side effects,which is worthy of widespread clinical promotion... |