Effects Of Frailty On Postoperative Cognitive Function And Perioperative Pain In Elderly Patients Undergoing Thoracoscopic Surgery

Objective: To explore Effects of frailty on postoperative cognitive function and perioperative pain in elderly patients undergoing thoracoscopic surgery.Methods: Select 168 cases of the first affiliated hospital of China medical university patients undergoing elective thoracoscope surgery under general anesthesia.The FRAIL scale was used to assess their frailty,and they were divided into frailty group(group F)and non-frailty group(group C).Two groups of narcotic drugs and the way of anesthesia are the same,induced initiated by the vertebral nerve block anesthesia,postoperative intravenous analgesia pump auxiliary treatment.Using simple mental state scale(MMSE)1 day record in patients with preoperative,postoperative 1 day,3 days,7 days ratings,and statistics within 7 days after two groups of postoperative cognitive dysfunction(POCD),postoperative with visual analogue scale(VAS)for patients with postoperative1 d and 2 d resting and coughing pain score.Results: The incidence of postoperative cognitive dysfunction in both groups were42.86% and 25.71% respectively,F group is higher than C group(P<0.05);MMSE score:preoperative 1 day,7 days after comparison,the two groups had no statistical significance;Postoperative day 1,day 3 more preoperative group C has decreased,but there was no statistically significant difference;Group F on postoperative day 1,day 3the preoperative decreased significantly,the difference was statistically significant(P<0.05);Postoperative day 1,day 3 F group were lower than that of group C,the difference was statistically significant(P<0.05);Two groups of postoperative day 1,day2 resting state of VAS score and cough,there was no statistically significant difference.Conclusion: Elderly patients who are debilitated before surgery have a high incidence of postoperative cognitive dysfunction(POCD).Frailty had no significant effect on perioperative pain.Thoracic paravertebral block combined with an intravenous analgesic pump can be safely used for post-thoracoscopic analgesia in elderly and debilitated patients.