| The goal of this study is to determine the clinical impact of a modified xiaochaihu decoction on the zonal postherpetic neuralgia syndrome of qi stagnation and blood stasis,as well as to compare changes in peripheral blood levels of CD4~+CD8~+T lymphocytes and patient quality of life before and after treatment.This information will be used to develop a method and idea for clinical treatment and medication.Methods:the criteria were fulfilled by 60 patients who were chosen.Two groups of patients were randomly divided into a control group and a treatment group,with 36 cases in each group,taking into account the possibility that some patients would be excluded or drop out during the trial.As a result,the selection was expanded by 20 persent,and a total of 72 patients were enrolled.While the control group received therapy with gabapentin capsules along with blood-letting puncture and cupping,the treatment group received a modified xiaochaihu decoction in addition to these procedures.The time frame of the medical care was four weeks.Before and after treatment,as well as at 1,2,3,and 4 weeks,the pittsburgh sleep quality index(PSQI),the VAS score,the pain duration score,the CD4~+and CD8~+T lymphocyte,the adverse events table,and the follow-up for a month after therapy were all recorded.SPSS 27.0 has been employed to collect and evaluate the data.Results:out of the 72 cases,68 were successfully treated,and 4 were lost.The findings of a statistical analysis were as follows:1.A comparison of VAS scores revealed a substantial difference between the two groups’VAS scores following treatment(P<0.01),according to statistical analysis data.After the first and second weeks of treatment,there was no discernible difference between the treatment group and the control group(P>0.05).However,at the third and fourth weeks of treatment,there was a discernible difference between the two groups(P<0.05).It is hypothesized that the treatment group’s improvement in pain intensity is better than that of the control group’s.2.Comparison of pain duration:the findings demonstrate that there was a statistically significant difference between the two groups’pain durations over the amplitude of the comparison(P<0.01)based on the statistical analysis of the data from the two groups’pain durations.After two weeks of treatment,there was no discernible difference between the two groups(P>0.05).It was hypothesized that after two weeks of treatment,neither group’s pain intensity had substantially decreased.The length of pain in the two groups was substantially different(P<0.05)after 3 and 4 weeks of treatment.It is hypothesized that the treatment group’s ability to reduce pain more quickly than the control group is better.3.Pittsburgh sleep quality index(PSQI):after statistical analysis of the data from the two groups’PSQI scores,in accordance with the experimental data,there was an ultimately reduced significant difference between the two full participants.After 3 weeks of treatment,there was no discernible difference between the two groups(P>0.05).After three weeks of therapy,it was suggested that there was little disparity between the two groups’sleep quality.Following a 4-week treatment course,the variation was statistically significant(P<0.05).It is hypothesized that as the ailment gets better,PHN patients’sleep quality will also improve.4.There were significant variations between the two groups before and after treatment(P<0.01)and after treatment for 4 weeks(P<0.05)in terms of the ratio of CD4~+to CD8~+T lymphocytes.Both groups were said to be able to enhance the patients’immune systems,though the treatment group’s enhancement was thought to be better than that of the control group.5.The overall effective rate in the treatment group was 97.05 percent,compared to82.35percent,in the control group.There was a strong correlation(P<0.05)between the two broad categories.Conclusion:the treatment group’s curative impact is comparable to that of the control group.6.Withdrawal symptoms:the vital signs,as well as the liver and kidney functio ns of the patients in both groups,were not obviously abnormal before and after tre atment,during the perioperative period,one patient in the group that received the s urgery started complaining of dry mouth,vertigo,and sleepiness.Considering the medic ation’s detrimental consequences,the patient was hesitant to continue taking it.Clearl y,the signs improved once the drug use was stopped.The frequency of adverse re actions did not significantly vary between the two groups(P>0.05).It was claimed that the control group’s medication safety was lower than that of the treatment grou p’s and the control group’s.7.Recurrence rate:patients were monitored for a month following psychotherapy.In the treatment group and control group,there were 0 and 2 recurrence cases,respectively.Both the treatment group and the control group may be competent to effectively control the disease,as there was no discernible difference in the recurrence rate here between the two groups(P>0.05).Conclusion:clinical symptoms of PHN patients with qi stagnation and blood stasis syndrome can be dramatically enhanced with the use of jiawei xiaochaihu decoction,blood-letting puncture,and cupping therapy,as well as gabapentin capsules,blood-letting puncture,and cupping therapy.But nevertheless,jiawei xiaochaihu decoction combined with blood-letting puncture and cupping is superior to gabapentin capsules combined with blood-letting puncture and cupping because it has a longer-lasting muscle spasm effect and can improve the quality of life,immunity,and recurrence rate of PHN patients.For the treatment of PHN with qi stagnation and blood stasis syndrome,it is suggested that a modified xiaochaihu decoction combined with blood-letting punctures and cupping therapy is more effective. |
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