Research On The Efficacy Of Unicorn Acne Treatment Instrument In The Treatment Of Moderate To Severe Acne

Objective:To compare the clinical efficacy of the unicorn acne treatment instrument and fire acupuncture in the treatment of moderate to severe acne and to evaluate the safety of the unicorn acne treatment instrument,with the aim of providing some clinical reference.Methods:This prospective faceted randomized controlled clinical trial for the treatment of patients with moderate to severe acne vulgaris.The right and left faces of 26 patients were randomly assigned to a treatment group(treated with the unicorn acne treatment device at weeks 0 and 4,receiving a total of 2 treatments)and a control group(treated with fire acupuncture at weeks 0 and 4,receiving a total of 2 treatments).For the evaluation of efficacy,the number of various types of acne lesions in patients at 0,1,2,4,8,and 12 weeks was recorded by the same physician.At the end of the first treatment operation,patients were required to receive pain ratings for both treatment modalities,and the satisfaction ratings of both treatments were conducted at the final follow-up.The adverse reactions that occurred in patients throughout the experimental period were observed and recorded,and statistical data were compared and analyzed.Results:1.Baseline comparison: The 26 patients enrolled completed this study.The differences in the number of lesions in each category and the total number of lesions were not statistically significant(P > 0.05)between the unicorn acne treatment instrument treatment side(treatment group)and the fire acupuncture treatment side(control group)when compared at baseline prior to treatment and were comparable.2.Intra-group analysis: After both methods of treatment,the number of lesions in both groups at each time point was compared with the number of lesions before treatment,and the number of lesions of each type and total lesions showed a decreasing trend with time,with statistically significant differences(P < 0.05).The treatment group showed a significant decrease(P < 0.05)in the number of lesions in the first week for pimples,papules,pustules,nodules/cysts and total lesions,while the control group showed a significant decrease(P < 0.05)in the number of lesions in the first week for pimples and total lesions,and a significant decrease(P < 0.05)in the number of lesions in the second week for papules,pustules and nodules/cysts.3.Intergroup analysis: Comparing the number of various types of lesions and the total number of lesions in the two groups,the differences in the number of papules,pustules and total lesions between the two groups were statistically significant(P <0.05),while the differences in the number of pimples and nodules/cysts were not statistically significant(P > 0.05).Further analysis of the interaction effect of time point and treatment modality showed that the interaction effect of time point and treatment modality was significant(P < 0.05)for the number of papules,pustules,nodules/cysts,and total lesions,except for pimples,meaning that the trend of the number of papules,pustules,nodules/cysts and total lesions of patients with time point would be different depending on the treatment modality.4.Comparison of efficiency: Except for pimples lesions(65.38% in the treatment group and 46.15% in the control group,P > 0.05,no statistically significant difference),for papules,pustules,nodules/cysts and total lesions,the efficiency of the treatment group(73.08%,80.77%,69.23%,76.92%,respectively)was higher than that of the control group(42.31%,46.15%,38.46%,38.46%),and the difference were statistically significant(P < 0.05).5.Comparison of pain degree: The pain degree scores of the subjects in both groups was lower in the treatment group than in the control group,and the difference was statistically significant(P < 0.05).6.Comparison of satisfaction: When comparing the satisfaction of the subjects in the two groups,the satisfaction scores of patients in the treatment group were higher than those in the control group,and the difference was statistically significant(P <0.05).7.Adverse reactions: To observe the adverse reactions in the two groups,14 patients in the control group had immediate bleeding during treatment,3 patients had post-treatment facial edema,and 2 patients had post-inflammatory hyperpigmentation;2 patients in the treatment group had a small amount of bleeding during treatment and3 patients had post-treatment facial edema.The incidence of adverse reactions in the treatment group was 6.41%,which was lower than 24.36% in the control group,and the difference was statistically significant(P < 0.05).All patients had pain during treatment and temporary post-treatment erythema on both sides of the face,and no serious adverse reactions such as secondary infection and scarring occurred.Conclusion:1.The unicorn acne treatment device and the fire target are effective on pimples,papules,pustules,nodules/cysts of moderate to severe acne.2.Compared to the fire target,the unicorn acne treatment instrument shows advantages in papules,pustules,and nodules/cysts lesions of moderate to severe acne,with fast onset and high efficiency for patients,but for pimples treatment,the unicorn acne treatment instrument has no significant advantages.3.Overall,compared to the fire target,the unicorn acne treatment device is highly effective in treating patients with moderate to severe acne,with fewer adverse effects,less subjective pain and higher satisfaction.Choosing the unicorn acne treatment device to treat moderate to severe acne is an effective and safe method.