| Objective:Based on the renal diagram ratio,the single renal bilateral plasma method of glomerular filtration rate（dGFR）,analyzes the multi-parameter of the renal renal renal diagram section of the nuclein renal dynamic appearance,and it is related to it.The best time period,and evaluate the effectiveness of various parameters of the single renal functionMethod:Looking back at the patients who have collected the nuclear-renal dynamic visibility and dual plasma method to determine the GFR of our hospital’s nuclear medical science,using the SPECT（Symbia T16）"Renal GFR Processes"program to re-draw the interested area of the kidneys and the bottom of the base,and get it The GFR（gGFR）determined by the double kidney and kidney diagram and Gates method,a total of 537 patients with a single kidney or kidney image agglomerate at the time of the kidney diagram function,a total of 977 cases of kidney and kidney diagram.Record each patient with a full needle and empty dose,and standardize the injection dose at 4m Ci.In the kidney diagram curve,record three time points of the kidney diagram convergence section:peak counting rate The 1min count rate before the peak value,the 2min counting rate before the peak time,and counting the counting rate change rate from 1min to peak and before the peak period and the peak time before the peak（referred to as slope 1 and slope 2）.Based on the kidney ratio of kidney dynamic visual renal diagrams,the single kidney dGFR value is obtained,and the patient is divided into 4 levels:level 0（good kidney function）:single kidney dGFR≥40 ml·min-1·1.73m-2;Grade Ⅰ（Mild Dempermia of Renal function）:40>Single kidney dGFR≥30 ml·min-1·1.73m-2;level Ⅱ（damage to kidney skills）:30>Single kidney dGFR≥20 ml·Min-1·1.73m-2;level Ⅲ（severe damage to kidney function and extremely severe weight）:20 ml·min-1·1.73m-2>single kidney dGFR.The parameters of the renal dynamic imaging kidney diagram are analyzed with the single kidney dGFR value respectively;the single kidney dGFR grading is the reference standard,and the best grading intercepting value corresponding to various parameters is found,and it is judged by the single kidney dGFR grading Consistency.Using single factor variance analysis,Pearson correlation analysis,ROC curve analysis,and Kappa consistency test analysis data.Result:1.Single kidney dGFR value and peak counting rate,peak 1min count rate,2min counting rate before peaks,slope rate 1.Slimming rate 2 presents significant linear relationships（P<0.001）,and the Pearson correlation coea R is 0.803,respectively.,0.789,0.788,0.639,0.681.2.Based on the single renal dGFR grading as the standard,the above five parameter ROC analyzes the grading of the best judgment of the single renal function:（1）The peak counting rate:level 0（≥175）,level Ⅰ（≥169,<175）is,Ⅱ（≥91,<169）,Ⅲ level（<91）,the best grading intercept point corresponds to Jon Deng Deng Deng The index is 0.341,0.323,0.594;（2）1Min counting rate before the Single Sandin Peak:Level 0（≥169）,level Ⅰ（≥121,<169）,Ⅱ（≥85,<121）as,Ⅲ（<85）,the best grading intercept point corresponds to the corresponding point corresponding to the corresponding point corresponding to the corresponding point The Joden Index is 0.323,0.434,0.578;（3）The 2min counting rate before the Single Sanples:Level 0（≥184）,level Ⅰ（≥133,<184）,Ⅱ（≥79,<133）is,Ⅲ（<79）,the best interception value corresponds to the appointment of the appointment value The login index is 0.245,0.438,0.545;（4）Slipping rate from 1min to peak before peak time:level 0（≥9）,level Ⅰ（≥6,<9）,Ⅱ（≥4,<6）as,Ⅲ（4）,the best interception value corresponds The Joden Index is 0.272,0.474,0.464,respectively;（5）Slipping rate from 2min to peaks before peak time:level 0（≥14）,level Ⅰ（≥10,<14）,Ⅱ（≥5,<10）as,Ⅲ（<5）,the best interception value corresponds The Joden Index is0.23、0.418、0.504,respectively.3.The above five parameters predict the Kappa value of the single renal function grading and the single renal dGFR grading consistency index of 0.628,0.616,0.584,0.558,and 0.538,respectively.Conclusion:1.The peak counting rate of the renal dynamic imaging kidney diagram,the 1min counting rate before the peak,the 2min counting rate before the peak,the slope of the peak from 1min before the peak time,the five indicators of the two-to-peak period from the peak from the peak time to the peak period are both and the single kidney.The dGFR value has a good correlation,of which the peak counting rate is the highest.2.Based on the Gates formula,the renal dynamic imaging kidney diagram can be used as the best time period for kidney intake before 1min during the peak of the peak,which can optimize the accuracy of gGFR.3.The peak counting rate of the renal dynamic appearance kidney diagram,the 1min counting rate before the peak,and the single renal dGFR judgment that the renal function is better consistent.The peak slope and the single kidney dGFR judge the medium of kidney function.Five parameters have increased according to the trend of single renal functional grading,and the accuracy of discrimination rises. |
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